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Cytomegalovirus (CMV) (from cyto-'cell' via Greek κύτος kútos - 'container' + μέγας mégas 'big, megalo-' + -virus via Latin vīrus 'poison') is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, [3] in the subfamily Betaherpesvirinae. Humans and other primates serve as natural hosts.
People infected with CMV develop antibodies to it, initially IgM later IgG indicating current infection and immunity respectively. The virus can be diagnosed through viral isolation, or using blood, urine, or saliva samples. [3] When infected with CMV, most women have no symptoms, but some may have symptoms resembling mononucleosis.
CMV infection or reactivation in people whose immune systems are compromised—for example people who have received transplants or are significantly burned—causes illness and increases the risk of death. [36] [37] CMV reactivation is commonly seen in people with severe colitis. [38] Specific disease entities recognized in those people are
Cucumber mosaic virus, of the family Bromoviridae Cytomegalovirus , a genus in the family Herpesviridae Human cytomegalovirus , a human-infecting species of cytomegalovirus commonly known as CMV
Panine betaherpesvirus 2 (PnHV-2) is a species of virus in the genus Cytomegalovirus, subfamily Betaherpesvirinae, family Herpesviridae, and order Herpesvirales. [1] [2] Chimpanzees serve as natural hosts.
Cytomegalovirus esophagitis is a form of esophagitis associated with cytomegalovirus. [1] Symptoms include dysphagia , upper abdominal pain, diarrhea, nausea, vomiting, and sometimes hematemesis . This condition occurs in the setting of patients with a weakened immune system who are susceptible to both infections by CMV and the manifestation of ...
CMV colitis may be clinically manifested with diarrhea (usually non-bloody), abdominal pain, weight loss and anorexia. The diagnosis of CMV colitis is based on serology, CMV antigen testing and colonoscopy with biopsy. Clinical suspicion should be aroused in the setting of immunocompromised patient but it is much rarer in immunocompetent patient.
Human cytomegalovirus (HCMV, HHV-5) "seems to have a large impact on immune parameters in later life and may contribute to increased morbidity and eventual mortality." [ 5 ] Human herpesvirus 6A (HHV-6A) has been described as more neurovirulent, [ 6 ] and as such is more frequently found in patients with neuroinflammatory diseases such as ...