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  2. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    The result is that apixaban generics will most likely not be available in the United States until at least 2026, but possibly 2031. [18] In July 2022, the Canadian generic drug company, Apotex Inc., obtained approval for marketing of apixaban. [39] [40] Pfizer reported revenue of US$6.747 billion for Eliquis in 2023. [41]

  3. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The p-methoxy group of apixaban connects to S1 pocket of FXa but does not appear to have any interaction with any residues in this region of FXa. The pyrazole N-2 nitrogen atom of apixaban interacts with Gln-192 and the carbonyl oxygen interacts with Gly-216. The phenyl lactam group of apixaban is positioned between Tyr-99 and Phe-174 and due ...

  4. Is Eliquis Covered by Medicare? - AOL

    www.aol.com/eliquis-covered-medicare-140000963.html

    Does Medicare cover Eliquis? ... If you qualify for Extra Help in 2024, you could pay no more than $4.50 for each generic covered drug and $11.20 for each brand-name covered drug.

  5. List of largest selling pharmaceutical products - Wikipedia

    en.wikipedia.org/wiki/List_of_largest_selling...

    apixaban: anticoagulant: Eliquis 1.6 3.0 4.6 7.1 9.9 3 etanercept: rheumatoid arthritis: Enbrel 7.2 7.6 ... Generic Name Sales Q1 2014 Sales ($000) Change from Q4 2013

  6. Fondaparinux - Wikipedia

    en.wikipedia.org/wiki/Fondaparinux

    Fondaparinux is a synthetic pentasaccharide factor Xa inhibitor. Fondaparinux binds antithrombin and accelerates its inhibition of factor Xa.. Apart from the O-methyl group at the reducing end of the molecule, the identity and sequence of the five monomeric sugar units contained in fondaparinux is identical to a sequence of five monomeric sugar units that can be isolated after either chemical ...

  7. FDA approves new pain medication as an alternative to opioids ...

    www.aol.com/news/fda-approves-pain-medication...

    The FDA on Thursday approved a new class of pain medication that provides an alternative to opioids. It will be sold under the brand name Journavx.

  8. These 2 Stocks Just Declared Dividend Raises That Kick In ...

    www.aol.com/finance/2-stocks-just-declared...

    Meanwhile, Opdivo and Eliquis will face the end of patent exclusivity in the waning years of this decade, so the company will be under pressure to either develop or acquire new blockbusters to at ...

  9. Authorized generics - Wikipedia

    en.wikipedia.org/wiki/Authorized_generics

    Authorized generics are prescription drugs produced by brand pharmaceutical companies and marketed under a private label, at generic prices. Authorized generics compete with generic products in that they are identical to their brand counterpart in both active and inactive ingredients; [1] whereas according to the U.S. Food and Drug Administration's Office of Generic Drugs, generic drugs are ...

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