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Ferric maltol was approved for medical use in the European Union in February 2016. [ 7 ] Ferric maltol was approved for medical use in the United States in July 2019, [ 6 ] [ 12 ] based on evidence from three clinical trials (trial 1/NCT01252221, trial 2/NCT01340872, [ 13 ] and trial 3/NCT02968368 [ 14 ] ). [ 5 ]
Ferric maltol, marketed as Accrufer [10] and Ferracru, is available in oral and intravenous preparations. When used as a treatment for IBD-related anemia, very low certainty evidence suggests a marked benefit with oral ferric maltol compared with placebo. However it was unclear whether the IV preparation was more effective than oral ferric ...
Geritol tablets. Geritol is a United States trademarked name for various dietary supplements, past and present. [1] Geritol is a brand name for several vitamin complexes plus iron or multimineral products in both liquid form and tablets containing from 9.5 to 18 mg of iron per daily dose. [2]
Ferrous sulfate is widely used for both prophylaxis and treatment of iron-deficiency anemia. [ 23 ] In 2018, it was the 94th most commonly prescribed drug in the United States, with over eight million prescriptions.
Ferric maltol, marketed as Accrufer and Ferracru, is available in oral and IV preparations. When used as a treatment for IBD-related anemia, very low certainty evidence suggests a marked benefit with oral ferric maltol compared with placebo. However it was unclear whether the IV preparation was more effective than oral ferric maltol. [70]
Efruxifermin (AKR-001) is an investigational drug developed by Akero Therapeutics, acting as a fibroblast growth factor 21 (FGF21) analog developed to treat metabolic dysfunction-associated steatohepatitis (MASH), formerly known as non-alcoholic steatohepatitis (NASH), and type 2 diabetes.
Iron deficiency, or sideropenia, is the state in which a body lacks enough iron to supply its needs. Iron is present in all cells in the human body and has several vital functions, such as carrying oxygen to the tissues from the lungs as a key component of the hemoglobin protein, acting as a transport medium for electrons within the cells in the form of cytochromes, and facilitating oxygen ...
An excipient is a substance formulated alongside the active ingredient of a medication.They may be used to enhance the active ingredient’s therapeutic properties; to facilitate drug absorption; to reduce viscosity; to enhance solubility; to improve long-term stabilization (preventing denaturation and aggregation during the expected shelf life); or to add bulk to solid formulations that have ...