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Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [4] It is used to treat peptic ulcer disease , gastroesophageal reflux disease , and Zollinger–Ellison syndrome . [ 4 ]
Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.
They are the most potent inhibitors of acid secretion available. The group followed and has largely superseded another group of pharmaceuticals with similar effects, but a different mode of action, called H 2-receptor antagonists. These drugs are among the most widely sold drugs in the world, and are generally considered effective. [3]
Subsequent to the introduction onto the U.S. drug market, two other H 2 receptor antagonists were approved, ranitidine (Zantac, Glaxo Labs) and famotidine (Pepcid, Yamanouchi, Ltd.) Cimetidine became the first drug ever to reach more than $1 billion a year in sales, thus making it the first blockbuster drug. [citation needed]
Pepcid RPD Scherer DDS / Merck: yes famotidine: Histamine H2-receptor antagonists [35] duodenal ulcer, gastric ulcer, gastroesophageal reflux disease, pathological hypersecretory conditions adults Prevacid SoluTab Takeda Pharmaceuticals: yes lansoprazole: Proton pump inhibitors [8] Gastro-oesophageal reflux disease (GERD), Ulcers [8] 1 year+ [8]
Too bad, otherwise it would be a GREAT idea to take for example 20mg of Famotidine with 400mg or 800mg ibuprofen painkiller. Unless one knows in advance that one has a headache and takes Famotidine first. As Ibuprofen increases stomach bleeding risk, Famotidine reduces this risk by about 50%? 91.159.189.212 14:34, 3 June 2023 (UTC)
This side effect was most common in guys who took 10 to 20 milligrams of Cialis a day. Tadalafil Side Effects Long-Term There are no known long-term side effects of tadalafil.
Common antacids include aluminum hydroxide/magnesium hydroxide (Maalox) and calcium carbonate (Tums). Histamine H2 blockers and proton pump inhibitors, such as famotidine (Pepcid) and omeprazole (Prilosec), respectively, can also be used to help relieve heartburn, with no known teratogenic effects or congenital malformations. [12]
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