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Gelclair is a medicinal oral gel containing polyvinylpyrrolidone (PVP) and hyaluronic acid [1] that coats the surface of the mouth forming a thin protective film over painful oral lesions, such as those caused by radiotherapy or chemotherapy treatment for cancer.
Symptomatic relief of the pain of oral mucositis may be provided by barrier protection agents such as concentrated oral gel products (e.g. Gelclair). Caphosol is a mouth rinse which has been shown to prevent and treat oral mucositis caused by radiation and high-dose chemotherapy.
Consistency and viscosity affect the adhesion and retention property of the gel, and are important in ensuring the gel is retained at the site of application and effective delivery of the drug. [ 3 ] The ingredients in topical gel formulation can be broadly categorized into four types: gelator, solvent, drug, and excipients.
Results released in February 2009 from a clinical trial of PRO 2000 (Indevus Pharmaceuticals), a vaginal-microbicide gel (0.5%), sparked hope that it might provide modest protection against HIV. [22] The results of a larger trial released in December 2009 showed that PRO 2000 was safe as administered, but was ineffective in reducing the risk of ...
The mouth is the only place in the body which provides the sensation of taste. Due to these unique physiological features, the oral mucosa must fulfil a number of distinct functions. Protection: One of the main functions of the oral mucosa is to physically protect the underlying tissues from the mechanical forces, microbes and toxins in the ...
A demulcent (derived from the Latin: demulcere "caress") is a mucilaginous or oleaginous preparation [1] that forms a soothing protective film over a mucous membrane, relieving minor pain and inflammation of the membrane. [2] However, they generally help for less than 30 minutes. [3] Demulcents are sometimes referred to as mucoprotective agents.
Bonjela packaging. Bonjela is a brand of oral treatments intended to relieve the pain of mouth ulcers and denture sores. The brand covers a range of products. Bonjela Adult and Cool are oral gels containing keratolytic and mildly antiseptic salicylic acid in the form of its salt choline salicylate and the antiseptic cetalkonium chloride as active ingredients.
Plastic cling wrap, condoms (repurposed by cutting off the tip and ring and cutting them lengthwise) or latex gloves (cut open longitudinally) can be used for STI protection in a similar manner as a dental dam, by providing a physical barrier to cover the vulvar or anal areas during oral sex and these alternative barrier methods are more ...
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