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Solitary mastocytoma, also known as cutaneous mastocytoma, may be present at birth or may develop during the first weeks of life, originating as a brown macule that urticates on stroking. [ 1 ] : 615 Solitary mastocytoma is a round, erythematous , indurated lesion measuring 1-5 cm in diameter.
Diagnosis and treatment are similar to that of the dog. Cases involving difficult to remove or multiple tumors have responded well to strontium-90 radiotherapy as an alternative to surgery. [28] The prognosis for solitary skin tumors is good, but guarded for tumors in other organs. Histological grading of tumors has little bearing on prognosis ...
Diagnosis of urticaria pigmentosa (cutaneous mastocytosis, see above) can often be done by seeing the characteristic lesions that are dark brown and fixed. A small skin sample may help confirm the diagnosis. [citation needed] In case of suspicion of systemic disease the level of serum tryptase in the blood can be of help.
M9740/1 Mastocytoma, NOS or Extracutaneous mastocytoma. Mast cell tumor, NOS; M9740/3 Mast cell sarcoma. Malignant mast cell tumor; Malignant mastocytoma; M9741/3 Malignant mastocytosis. Systemic tissue mast cell disease; Aggressive systemic mastocytosis or Systemic mastocytosis with associated clonal, hematological non-mast cell lineage disease
Mastocytoma: Abundant mast cells Tzanck smear test is useful for rapid diagnosis of mastocytoma in children Sebaceous hyperplasia: Clusters of sebocytes Seborrheic keratosis: Hyperkeratosis and horny cysts 87.5% sensitive and 80.8% specific Melanocytic nevi: Dermal and epidermal type nevoid cells 87.5% sensitive and 100% specific Eruptive ...
The majority of urticaria pigmentosa cases are caused by a point mutation at amino acid 816 of the proto-oncogene c-kit. [2] c-kit is a transmembrane protein which, when bound to Mast Cell Growth Factor (MCGF), signals the cell to divide.
[19] [20] Clinically, the diagnosis of any particular skin condition is made by gathering pertinent information regarding the presenting skin lesion(s), including the location (such as arms, head, legs), symptoms (pruritus, pain), duration (acute or chronic), arrangement (solitary, generalized, annular, linear), morphology (macules, papules ...
This is a shortened version of the second chapter of the ICD-9: Neoplasms.It covers ICD codes 140 to 239.The full chapter can be found on pages 101 to 144 of Volume 1, which contains all (sub)categories of the ICD-9.