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Injection site reactions (ISRs) are reactions that occur at the site of injection of a drug. They may be mild or severe and may or may not require medical intervention. Some reactions may appear immediately after injection, and some may be delayed. [1] Such reactions can occur with subcutaneous, intramuscular, or intravenous administration.
Restylane is the trade name for a range of injectable fillers with a specific formulation of hyaluronic acid (HA). In the United States, Restylane was the first hyaluronic acid filler to be approved by the U.S. Food and Drug Administration (FDA) for cosmetic injection into subdermal facial tissues. [1] Restylane is produced by Galderma.
In osteoarthritis, joint injection of glucocorticoids (such as hydrocortisone) leads to short term pain relief that may last between a few weeks and a few months. [5] Injections of hyaluronic acid have not produced improvement compared to placebo for knee arthritis, [6] [7] but did increase risk of further pain. [6]
Perhaps the most dire cause of knee swelling, infection in the knee joint warrants a hasty trip to the doctor. When an infection gets into the knee joint, “the knee quickly becomes really ...
Knee pain relief of 50% or more following genicular RFA may last from several months to two years, [129] [132] and can be repeated by the same outpatient procedure when pain recurs. [129] Injection of phenol may be used as a neurolytic treatment of sensory knee nerves to relieve chronic pain from knee osteoarthritis. [134] [135]
Non-surgical rhinoplasty is a medical aesthetic procedure in which injectable fillers, most commonly hyaluronic acid ones like Restylane and Juvederm or calcium hydroxyapatite (Radiesse), are used to alter and shape a person's nose without a surgery.
Knee effusion, informally known as water on the knee, occurs when excess synovial fluid accumulates in or around the knee joint. It has many common causes, including arthritis , injury to the ligaments or meniscus , or fluid collecting in the bursa , a condition known as prepatellar bursitis .
Prepatellar bursitis is an inflammation of the prepatellar bursa at the front of the knee. It is marked by swelling at the knee, which can be tender to the touch and which generally does not restrict the knee's range of motion. It can be extremely painful and disabling as long as the underlying condition persists.