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The dopamine hypothesis of schizophrenia or the dopamine hypothesis of psychosis is a model that attributes the positive symptoms of schizophrenia to a disturbed and hyperactive dopaminergic signal transduction. The model draws evidence from the observation that a large number of antipsychotics have dopamine-receptor antagonistic effects. The ...
It is thought that the psychotic symptoms within schizophrenia are primarily due to overactive dopamine activity in the mesolimbic area of the brain. [4] Therefore, dopamine supersensitivity may reduce the effect of antipsychotics and increase the brain's response to endogenous dopamine, leading to worsening psychosis. [4]
Substance avoidance can be important in reducing anxiety and panic symptoms, as many substances can cause, exacerbate, or mimic symptoms of panic disorder. For example, caffeine has been known to have anxiety and panic-inducing properties that can especially present in those who are more susceptible to panic attacks. [60]
Additionally, CNS dopamine signaling is active in heart rate, respiration and body temperature regulation. [22] Dopamine imbalance can hence result in hyperthermia, tachycardia, hyperventilation, hypertension and sleep disturbance symptoms. [6] [3]
Dopamine dysregulation syndrome (DDS) is a dysfunction of the reward system observed in some individuals taking dopaminergic medications for an extended length of time. It is characterized by severely disinhibited patterns of behavior, [1] leading to problems such as addiction to the offending medication, gambling addiction, or compulsive sexual behavior, [2] along with a general orientation ...
It turns out that psychological issues can be amplified when taking Adderall, so a person with anxiety or depression could feel worse mental health symptoms. The contributors of a low intimacy ...
Stress can cause acute and chronic changes in certain brain areas which can cause long-term damage. [4] Over-secretion of stress hormones most frequently impairs long-term delayed recall memory, but can enhance short-term, immediate recall memory. This enhancement is particularly relative in emotional memory.
Treats symptoms of anxiety and depression Fluoxetine: Serotonin (5-HT) supports 5-HT reuptake SSRI Inhibits reuptake of serotonin Treats depression, some anxiety disorders, and OCD [64] Common examples: Prozac and Sarafem. Fenfluramine: Serotonin (5-HT) – – Causes release of serotonin Inhibits reuptake of serotonin Used as an appetite ...