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Xenotransplantation (xenos-from the Greek meaning "foreign" or strange [1] [2]), or heterologous transplant, is the transplantation of living cells, tissues or organs from one species to another. [3] Such cells, tissues or organs are called xenografts or xenotransplants .
Xenotransplantation is a cross-species tissue transplantation from animal to human. [10] [11] The development of blood vessel anastomosis opened the door for xenotransplantation during the 20th century, which led to numerous attempts in organ transplantations with tissues from nonhuman primates (NHPs).
It is a form of xenotransplantation. PDX models are used to create an environment that allows for the continued growth of cancer after its removal from a patient. In this way, tumor growth can be monitored in the laboratory, including in response to potential therapeutic options. [1]
Xenotransplantation is a bimonthly peer-reviewed medical journal covering xenotransplantation. It is published by Wiley-Blackwell and the editor-in-chief is Leo H. Bühler (University of Fribourg). The annual Carl-Gustav Groth Xeno Prize of US$7,000 is presented to the first author of the best article published in the journal. [1] [2]
Xenotransfusion (from Greek xenos-'strange, foreign'), a form of xenotransplantation, was initially defined as the transfer of blood from one species into the veins of another. [1] In most cases, it is a transfer of blood between a non-human animal and a human. However, further experimentation has been done between various non-human animal species.
However, xenotransplantation is often an extremely dangerous type of transplant because of the increased risk of non-functional compatibility, rejection, and disease carried in the tissue. In the opposite direction, attempts are being made to devise a way to transplant human fetal hearts and kidneys into animals for future transplantation into ...
Stephanie Fae Beauclair [1] (October 14, 1984 – November 15, 1984), better known as Baby Fae, was an American infant born in 1984 with hypoplastic left heart syndrome.She became the first infant subject of a xenotransplant procedure and first successful infant heart transplant, receiving the heart of a baboon.
Dhaniram Baruah is an Indian heart surgeon from Assam, known for his work in the field of xenotransplantation.He is popularly known as India's Pig Heart Doctor. [1] On 1 January 1997, he became the first heart surgeon in the world to transplant a pig's heart in a human body. [2]