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Ocrelizumab, sold under the brand name Ocrevus, is a medication used for the treatment of multiple sclerosis.It is a humanized anti-CD20 monoclonal antibody. [8] It targets CD20 marker on B lymphocytes and is an immunosuppressive drug. [10]
In March 2017, ocrelizumab was approved in the United States for the treatment of primary progressive multiple sclerosis in adults. [22] [42] It is also used for the treatment of relapsing forms of multiple sclerosis, to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease in adults. [42]
In the United States, as of 2015, the cost is between US$1,284 and US$1,386 per 30 mcg vial. [31] As of 2020, the National Average Drug Acquisition Cost (NADAC) in the United States for Avonex was $6,872.94 for a 30 mcg kit. [32] Avonex and Rebif are on the top ten best-selling multiple sclerosis drugs of 2013. [33]
Multiple sclerosis (MS) is an autoimmune disorder in which the immune system attacks and destroys the myelin sheath of nerve cells. It most commonly strikes people between the ages of 20 and 40.
For each of the four type of MS, early diagnosis and treatment are key to slowing its progression. Skip to main content. 24/7 Help. For premium support please call: 800-290-4726 ...
A three-year controlled study of 60 patients is now being launched at 10 centres across the UK. [119] In another clinical trial, glatiramer acetate (Copaxone) has been combined with mitoxantrone in such a way that every course of mitoxantrone is followed by GA treatment. It has yielded promising results twice, in a consistent way. [120] [121]
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