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The peptides can be specially designed for specificity. A single peptide vaccine can be designed to have multiple epitopes to generate immune responses for several diseases. The vaccines only contain a short peptide chain, so they are less like to lead to allergic or auto-immune responses. Disadvantages: Poor immunogenicity. Unstable in cells.
Peptide therapeutics are peptides or polypeptides (oligomers or short polymers of amino acids) which are used to for the treatment of diseases. Naturally occurring peptides may serve as hormones , growth factors , neurotransmitters , ion channel ligands , and anti-infectives ; peptide therapeutics mimic such functions.
Two, peptide drugs are more expensive than small molecule drugs to produce, which is problematic since peptide drugs must be given in large doses to counter rapid enzymatic breakdown. These qualities also limit routes of administration, typically to injection, infusion, or slow release therapy. [39]
Most type 2 diabetes injections for weight loss are glucagon-like peptide-1 (GLP-1) receptor agonists. These drugs mimic the GLP-1 hormone, which is made in your gastrointestinal tract when you ...
Liraglutide is a glucagon-like peptide-1 receptor agonist (GLP-1 receptor agonist) also known as incretin mimetics. [6] It works by increasing insulin release from the pancreas and decreases excessive glucagon release. [6] Common side effects include low blood sugar, nausea, dizziness, abdominal pain, and pain at the site of injection.
[11] [17] Tirzepatide is administered via subcutaneous injections (under the skin). [10] [14] It is sold under the brand name Mounjaro for diabetes treatment, [10] and Zepbound for weight loss and treatment of obstructive sleep apnea. [11] [18] Tirzepatide is a gastric inhibitory polypeptide analog and GLP-1 receptor agonist. [11]
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