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  2. Bezlotoxumab - Wikipedia

    en.wikipedia.org/wiki/Bezlotoxumab

    Bezlotoxumab is indicated to reduce recurrence of Clostridioides difficile infection in people who are receiving antibacterial drug treatment for Clostridioides difficile infection and are at a high risk for Clostridioides difficile infection recurrence. [3]

  3. Clostridioides difficile infection - Wikipedia

    en.wikipedia.org/wiki/Clostridioides_difficile...

    Clostridioides difficile infection [5] (CDI or C-diff), also known as Clostridium difficile infection, is a symptomatic infection due to the spore-forming bacterium Clostridioides difficile. [6] Symptoms include watery diarrhea, fever, nausea, and abdominal pain. [1] It makes up about 20% of cases of antibiotic-associated diarrhea. [1]

  4. Clostridioides difficile toxin B - Wikipedia

    en.wikipedia.org/wiki/Clostridioides_difficile...

    Bezlotoxumab is a human monoclonal antibody designed for the prevention of recurrence of Clostridium difficile infections. By x-ray crystallized structure of N-terminal of TcdB, the toxin is identified to consist of three domains: a glucosyltransferase domain (GTD), a cysteine protease and a combined repetitive oligopeptide (CROP) domain.

  5. Fecal microbiota transplant - Wikipedia

    en.wikipedia.org/wiki/Fecal_microbiota_transplant

    FMT is an effective treatment for Clostridioides difficile infection (CDI). [3] [4] [5] For recurrent CDI, FMT is more effective than vancomycin alone, and may improve the outcome after the first index infection. [3] [5] [6] Side effects may include a risk of infections, therefore the donor should be screened for pathogens. [7]

  6. Clostridioides difficile - Wikipedia

    en.wikipedia.org/wiki/Clostridioides_difficile

    Clostridioides difficile (syn. Clostridium difficile) is a bacterium known for causing serious diarrheal infections, and may also cause colon cancer. [4] [5] It is known also as C. difficile, or C. diff (/ s iː d ɪ f /), and is a Gram-positive species of spore-forming bacteria. [6]

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  8. Antibiotic-associated diarrhea - Wikipedia

    en.wikipedia.org/wiki/Antibiotic-associated_diarrhea

    Clostridioides difficile, also known more commonly as C. diff, accounts for 10 to 20% of antibiotic-associated diarrhea cases, because the antibiotics administered for the treatment of certain disease processes such as inflammatory colitis also inadvertently kill a large portion of the gut flora, the normal flora that is usually present within the bowel.

  9. Dying To Be Free - The Huffington Post

    projects.huffingtonpost.com/dying-to-be-free...

    This disciplinary proceeding drew from the spirit of the Synanon Game, and it fed off the mutual suspicion and instinct for punishment that have become ingrained in drug treatment. Grateful Life holds these trials, what the staff calls “Community,” several times per week. Each session can last as long as two hours.

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