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  2. Innate immune system - Wikipedia

    en.wikipedia.org/wiki/Innate_immune_system

    The innate immune system or nonspecific immune system [1] is one of the two main immunity strategies in vertebrates (the other being the adaptive immune system). The innate immune system is an alternate defense strategy and is the dominant immune system response found in plants , fungi , prokaryotes , and invertebrates (see Beyond vertebrates ).

  3. Clonal selection - Wikipedia

    en.wikipedia.org/wiki/Clonal_selection

    He further formalised the theory in his 1959 book The Clonal Selection Theory of Acquired Immunity. He explained immunological memory as the cloning of two types of lymphocyte. One clone acts immediately to combat infection whilst the other is longer lasting, remaining in the immune system for a long time and causing immunity to that antigen.

  4. Nonspecific immune cell - Wikipedia

    en.wikipedia.org/wiki/Nonspecific_immune_cell

    Non-specific immunity, or innate immunity, is the immune system with which you were born, made up of phagocytes and barriers. Phagocytosis , derived from the Greek words phagein , meaning to eat, kytos or cell, and “osis” meaning process, was first described by Élie Metchnikoff , who won the Nobel Prize 100 years ago.

  5. Immune system - Wikipedia

    en.wikipedia.org/wiki/Immune_system

    The immune system is involved in many aspects of physiological regulation in the body. The immune system interacts intimately with other systems, such as the endocrine [83] [84] and the nervous [85] [86] [87] systems. The immune system also plays a crucial role in embryogenesis (development of the embryo), as well as in tissue repair and ...

  6. Immunology - Wikipedia

    en.wikipedia.org/wiki/Immunology

    Immunology is a branch of biology and medicine [1] that covers the study of immune systems [2] in all organisms.. Immunology charts, measures, and contextualizes the physiological functioning of the immune system in states of both health and diseases; malfunctions of the immune system in immunological disorders (such as autoimmune diseases, hypersensitivities, [3] immune deficiency, [4] and ...

  7. Immunological memory - Wikipedia

    en.wikipedia.org/wiki/Immunological_memory

    Despite not having the ability to manufacture antibodies like the adaptive immune system, innate immune system has immune memory properties as well. Innate immune memory (trained immunity) is defined as a long-term functional reprogramming of innate immune cells evoked by exogenous or endogenous insults and leading to an altered response ...

  8. Pathogen-associated molecular pattern - Wikipedia

    en.wikipedia.org/wiki/Pathogen-associated...

    This allows the innate immune system to recognize pathogens and thus, protect the host from infection. [ 3 ] : 494 Although the term "PAMP" is relatively new, the concept that molecules derived from microbes must be detected by receptors from multicellular organisms has been held for many decades, and references to an "endotoxin receptor" are ...

  9. Immunity (medicine) - Wikipedia

    en.wikipedia.org/wiki/Immunity_(medicine)

    Innate immunity, also known as native immunity, is a semi-specific and widely distributed form of immunity. It is defined as the first line of defense against pathogens, representing a critical systemic response to prevent infection and maintain homeostasis, contributing to the activation of an adaptive immune response. [ 4 ]