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Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
Doxylamine is used in the combination drug pyridoxine/doxylamine to treat morning sickness (nausea and vomiting of pregnancy). [ 19 ] [ 20 ] [ 21 ] It is the only medication approved by the United States Food and Drug Administration for the treatment of morning sickness.
Although described as "morning sickness," pregnant women can experience this nausea any time of day or night. The exact cause of morning sickness remains unknown. Nausea and vomiting in pregnancy is typically mild and self-limited, resolving on its own by the 14th week of pregnancy. Other causes should also be ruled out when considering treatment.
Previous studies have suggested sickness and nausea in pregnancy could relate to GDF15 being produced by the placenta, but researchers said the “full mechanistic understanding is lacking”.
Some have proposed that morning sickness may be useful from an evolutionary point of view. [1] Diagnosis should only occur after other possible causes have been ruled out. [3] Abdominal pain, fever, or headaches are typically not present in morning sickness. [1] Morning sickness affects about 70–80% of all pregnant women to some extent.
Hyperemesis gravidarum tends to occur in the first trimester of pregnancy [17] and lasts significantly longer than morning sickness. While most women will experience near-complete relief of morning sickness symptoms near the beginning of their second trimester , some people with HG will experience severe symptoms until they give birth to their ...
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Duchess Kate suffering from severe morning sickness with baby No. 3. Maya Chung. ... She was hospitalized due to Hyperemesis gravidarum while she was a few weeks pregnant with Prince George in 2012.
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