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Methylprednisolone succinate, sold under the brand name Solu-Medrol among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester—specifically the C21 succinate ester of methylprednisolone—which is used by intravenous administration.
Depo-Medrol is available as sterile aqueous solution in 20 mg/mL, 40 mg/mL, or 80 mg/mL strengths. [23] Solu-Medrol is the only derivative of methylprednisolone that is approved for intravenous infusion, as the sterile powder is soluble in water and can be mixed with a diluent. Strengths vary from 40 mg to 2 g. [22]
IV infusion: Day 0 Etoposide: 40 mg/m 2: IV infusion over 1 hr: Days 1-4 Solu-Medrol - Methylprednisolone: 500 mg: IV bolus over 15 min: Days 1-5 High-dose Ara-C — cytarabine: 2000 mg/m 2: IV infusion over 2 hrs: Day 5 Platinol (cisplatin) 25 mg/m 2: IV continuous infusion over 24 hrs: Days 1-4
Once a diagnosis of JDMS is made, the treatment is often a 3-day course of Intravenous ("pulse") steroids (methylprednisolone, Solu-Medrol), followed by a high dose of oral prednisone (usually 1–2 mg/kg of body weight) for several weeks. This action usually brings the disease under control, lowering most lab tests to or near normal values.
50. South Dakota. Average price per child: $247 This article was originally published on Cheapism
Tesla and SpaceX CEO Elon Musk speaks with Donald Trump during a campaign event at the Butler Farm Show, Saturday, Oct. 5, 2024, in Butler, Pa.
How are you holding up? Are you over it? I'm over it. I'm fine. At least, at times I think that. It's obviously not what I wanted but that's life.
A bolus delivered directly to the veins through an intravenous drip allows a much faster delivery which quickly raises the concentration of the substance in the blood to an effective level. This is typically done at the beginning of a treatment or after a removal of medicine from blood (e.g. through dialysis ).