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Peroxisomes also play a role in the production of bile acids important for the absorption of fats and fat-soluble vitamins, such as vitamins A and K. Skin disorders are features of genetic disorders affecting peroxisome function as a result. [17] The specific metabolic pathways that occur exclusively in mammalian peroxisomes are: [5]
Peroxins serve several functions including the recognition of cytoplasmic proteins that contain peroxisomal targeting signals (PTS) that tag them for transport by peroxisomal proteins to the peroxisome.
A peroxisome is a type of microbody that functions to help the body break down large molecules and detoxify hazardous substances. It contains enzymes like oxidase, react hydrogen peroxide as a byproduct of its enzymatic reactions. Within the peroxisome, hydrogen peroxide can then be converted to water by enzymes like catalase and peroxidase.
224824 Ensembl ENSG00000124587 ENSMUSG00000002763 UniProt Q13608 Q99LC9 RefSeq (mRNA) NM_000287 NM_001316313 NM_145488 RefSeq (protein) NP_000278 NP_001303242 NP_663463 Location (UCSC) Chr 6: 42.96 – 42.98 Mb Chr 17: 47.02 – 47.04 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Peroxisome assembly factor 2 is a protein that in humans is encoded by the PEX6 gene. PEX6 is an AAA ...
103737 Ensembl ENSG00000108733 ENSMUSG00000018733 UniProt O00623 Q8VC48 RefSeq (mRNA) NM_000286 NM_134025 NM_001364762 NM_001364763 RefSeq (protein) NP_000277 NP_598786 NP_001351691 NP_001351692 Location (UCSC) Chr 17: 35.57 – 35.58 Mb Chr 11: 83.19 – 83.19 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Peroxisome assembly protein 12 is a protein that in humans is encoded by the ...
Peroxisome biogenesis factor 10 is a protein that in humans is encoded by the PEX10 gene. [ 5 ] [ 6 ] Alternative splicing results in two transcript variants encoding different isoforms. Function
Peroxisome biogenesis factor 1, also known as PEX1, is a protein which in humans is encoded by the PEX1 gene. [ 5 ] This gene encodes a member of the AAA protein family, a large group of ATPases associated with diverse cellular activities.
74043 Ensembl ENSG00000215193 ENSMUSG00000067825 UniProt Q7Z412 Q8BGI5 RefSeq (mRNA) NM_017929 NM_001127649 NM_001199319 NM_028730 NM_001304773 NM_001304774 RefSeq (protein) NP_001121121 NP_001186248 NP_060399 NP_001121121.1 NP_060399.1 NP_001291702 NP_001291703 NP_083006 Location (UCSC) Chr 22: 18.08 – 18.11 Mb Chr 6: 121.16 – 121.18 Mb PubMed search Wikidata View/Edit Human View/Edit ...