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The insulin aspart protamine portion is a crystalline form of insulin aspart, which delays the action of the insulin, giving it a prolonged absorption profile after injection. [14] The combination of the fast-acting form and the long-acting form allows the patient to receive fewer injections over the course of the day.
The differences mean that insulin degludec is absorbed more slowly by the body. [6] This means it has a long duration of action. [6] Meanwhile, insulin aspart is absorbed faster by the body than human insulin, and therefore it starts to work as soon as it is injected and has a short duration of action. [6]
This calculation may also be performed by an insulin pump in patients using a pump. Insulin regiments that consist of doses calculated in this manner are considered intensive insulin regimens. [37] Prandial insulin is usually administered no more than 15–30 minutes prior to a meal using a rapid-acting insulin or a regular insulin.
ATC code A10 Drugs used in diabetes is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Insulin; Insulin analog; Insulin aspart; Insulin degludec; Insulin degludec/insulin aspart; Insulin degludec/liraglutide; Insulin detemir; Insulin efsitora alfa; Insulin glargine; Insulin glargine/lixisenatide; Insulin glulisine; Insulin icodec; Insulin icodec/semaglutide; Insulin lispro; Insulin (medication) Insulin tregopil; Insulin-like ...
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Insulin degludec was studied as an alternative to insulin glargine as part of a basal-bolus regimen in the BEGIN Basal-Bolus Type 1 trial. 629 participants with type 1 diabetes were randomized in a 3:1 ratio to either insulin degludec (n=472) or insulin glargine (n=157) in addition to mealtime insulin aspart. Participants in the degludec ...
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