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Alpha-gal syndrome (AGS), also known as alpha-gal allergy or mammalian meat allergy (MMA), [1] is a type of acquired allergy characterized by a delayed onset of symptoms (3–8 hours) after ingesting mammalian meat. The condition results from past exposure to certain tick bites and was first reported in 2002.
What is Alpha-gal syndrome? This potentially fatal condition gets its name from the molecule galactose-α-1,3-galactose (a.k.a. alpha-gal), which is found in most mammals.
Here’s everything you need to know about alpha-gal syndrome
Galactose-α-1,3-galactose, commonly known as alpha gal and the Galili antigen, is a carbohydrate found in most mammalian cell membranes. It is not found in catarrhines , [ 1 ] including humans, who have lost the GGTA1 gene.
Alpha-gal may refer to: Alpha-galactosidase, an enzyme; Galactose-alpha-1,3-galactose, a carbohydrate also known as Galili antigen; Alpha-gal allergy
Alpha-gal sounds like a sorority nickname, but it is short for the sugar galactose-alpha-1,3-galactose.
Pork–cat syndrome is an allergy to pork, usually after adolescence, that is related to cat allergy. Although first described in 1994, [1] [2] [3] it was first documented in the U.S. by Scott Commins and Thomas Platts-Mills during their research on alpha-gal allergy.
The areas where alpha-gal syndrome was most prevalent largely aligned with areas where the lone star tick is known to be established or reported. Between 2017 and 2021, the number of positive test ...