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Eosinophilia–myalgia syndrome is a rare, sometimes fatal neurological condition linked to the ingestion of the dietary supplement L-tryptophan. [1] [2] The risk of developing EMS increases with larger doses of tryptophan and increasing age. [3]
There are three types of lathyrism: neurolathyrism, osteolathyrism, and angiolathyrism, all of which are incurable, differing in their symptoms and in the body tissues affected. [ 1 ] Neurolathyrism is the type associated with the consumption of legumes in the genus Lathyrus that contain the toxin oxalyldiaminopropionic acid (ODAP).
β-Methylamino-L-alanine, or BMAA, is a non-proteinogenic amino acid produced by cyanobacteria. BMAA is a neurotoxin . Its potential role in various neurodegenerative disorders is the subject of scientific research.
Beta-Alanine, a nonessential amino acid and freely available as a nutritional supplement in many countries, has been found to suppress or significantly reduce the symptoms in many cases. [12] Anecdotal evidence indicates that it is commonly consumed in doses of 750 mg to 2 grams before water contact. [ 13 ]
The Cahill cycle, also known as the alanine cycle or glucose-alanine cycle, [1] is the series of reactions in which amino groups and carbons from muscle are transported to the liver. [2] It is quite similar to the Cori cycle in the cycling of nutrients between skeletal muscle and the liver. [ 1 ]
Ensure women are aware of their cancer profile early. "All women should know their cancer risk profile by the age of 30," Litvack says. "We all need to be in control of our own health, having the ...
Neurolathyrism, is a neurological disease of humans, caused by eating certain legumes of the genus Lathyrus.This disease is mainly associated with the consumption of Lathyrus sativus (also known as grass pea, chickling pea, kesari dal, or almorta) and to a lesser degree with Lathyrus cicera, Lathyrus ochrus and Lathyrus clymenum [1] containing the toxin ODAP.
ODAP is an agonist of the ionotropic [6] AMPA glutamate receptor. [5] It is known to cause neurolathyrism in humans, a motor neuron degenerative disease characterized by degeneration of pyramidal-tract neurons in the spinal cord and in the area of the cortex controlling the legs, resulting in lower-body paralysis. [6]