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Bone grafting is a surgical procedure that replaces missing bone in order to repair bone fractures that are extremely complex, pose a significant health risk to the patient, or fail to heal properly. Some small or acute fractures can be cured without bone grafting, but the risk is greater for large fractures like compound fractures.
Demineralized freeze dried bone allograft, referred to as DFDBA, is a bone graft material known for its de novo bone formation properties. [1] It is used extensively in bone grafting of alveolar bone in oral and periodontal surgery.
Demineralized bone matrix (DBM) is allograft bone that has had the inorganic mineral removed, leaving behind the organic "collagen" matrix. It was first discovered by Marshall Urist in 1965 that the removal of the bone mineral exposes more biologically active bone morphogenetic proteins . [ 1 ]
Artificial bone refers to bone-like material created in a laboratory that can be used in bone grafts, to replace human bone that was lost due to severe fractures, disease, etc. [1] Bone fracture, which is a complete or partial break in the bone, is a very common condition that has more than three million US cases per year. [ 2 ]
Albee was born on a farm in the township of Alna, Maine, on a Friday the 13th, and learned how to do tree grafting from his uncle, Charles Houdlette. [1] He later applied the principles of grafting, and guarding a tree from outside disruptions, to his bone grafting operations. Though he was a hard worker on the farm, he was fascinated by medicine.
When a bone fractures, the fragments lose their alignment in the form of displacement or angulation. For the fractured bone to heal without any deformity the bony fragments must be re-aligned to their normal anatomical position. Orthopedic surgery attempts to recreate the normal anatomy of the fractured bone by reduction of the displacement.
Prolonged use of an IO site, lasting longer than 24 hours, is associated with osteomyelitis (an infection in the bone). [3] Intraosseous infusion-- needle insertion into anterior tibia. The needle is inserted through the bone's hard cortex and into the soft marrow interior, which allows immediate access to the vascular system. The IO needle is ...
It can be used as a tissue replacement for repairing bony defects when autogenous bone graft is not feasible or possible. [21] [22] [23] It may be used alone or in combination with a biodegradable, resorbable polymer such as polyglycolic acid. [24] It may also be combined with autologous materials for a bone graft. [25] [26]