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Epinephrine is available in an autoinjector delivery system and a nasal spray. There is an epinephrine metered-dose inhaler sold over the counter in the United States to relieve bronchial asthma . [ 67 ] [ 68 ] It was introduced in 1963 by Armstrong Pharmaceuticals.
Taylor was known to have had allergies that congested her upper respiratory system and she used Primatene, an over-the-counter epinephrine inhaler, to combat shortness of breath. While epinephrine can cause cardiac arrhythmia , it was impossible to prove she had taken any just prior to her death.
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Injected epinephrine proved to be especially efficacious for the acute treatment of asthma attacks, and an inhaled version was sold in the United States until 2011 (Primatene Mist). [ 5 ] [ 6 ] By 1929 epinephrine had been formulated into an inhaler for use in the treatment of nasal congestion.
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