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DESeq2 is a software package in the field of bioinformatics and computational biology for the statistical programming language R. It is primarily employed for the analysis of high-throughput RNA sequencing (RNA-seq) data to identify differentially expressed genes between different experimental conditions.
For example, suppose that the values x are realizations from different Poisson distributions: i.e. the distributions each have different mean values μ. Then, because for the Poisson distribution the variance is identical to the mean, the variance varies with the mean. However, if the simple variance-stabilizing transformation
To determine whether normalization is needed, one can plot Cy5 (R) intensities against Cy3 (G) intensities and see whether the slope of the line is around 1. An improved method, which is basically a scaled, 45 degree rotation of the R vs. G plot is an MA-plot. [ 4 ]
In programming language semantics, normalisation by evaluation (NBE) is a method of obtaining the normal form of terms in the λ-calculus by appealing to their denotational semantics. A term is first interpreted into a denotational model of the λ-term structure, and then a canonical (β-normal and η-long) representative is extracted by ...
Oja's learning rule, or simply Oja's rule, named after Finnish computer scientist Erkki Oja (Finnish pronunciation:, AW-yuh), is a model of how neurons in the brain or in artificial neural networks change connection strength, or learn, over time.
Apple. Apple (NASDAQ:AAPL) is a company that people just love to doubt. The stock started 2024 with a pretty expensive multiple, only to end the year with an even pricier one (shares go for almost ...
The scents of cinnamon and star anise add big flavors to this quick soup. Butter adds body and a silky texture. Fresh udon noodles take only a few minutes to cook, but dry udon noodles work well ...
Get ready for the final full moon of 2024: the Cold Moon. Skywatchers who want to see it at its fullest should be prepared to head out this weekend — the December full moon will reach peak ...