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A test-retest reproducibility PET study indicates that [11 C]DASB can be used to measure the serotonin transporter parameters with high reliability in receptor-rich brain regions. [ 4 ] When the DASB neuroimages are analyzed the kinetic models suggested by Ichise and coworkers [ 12 ] can be employed to estimate the binding potential .
The Utah 3D Animation Repository, a small collection of animated 3D models; scene collection, by Physically Based Rendering Toolkit: a number of interesting scenes to render with global illumination; MGF Example Scenes, a small collection of some indoor 3D scenes; archive3D, a collection of 3D models; 3DModels, a collection of vehicle 3D models
Cell group B9 is a group of cells located in the pontine tegmentum, ventral to serotonergic group B8.In the nonhuman primate they are found in the ventral part of the superior central nucleus and adjacent structures. [3]
A serotonin pathway identifies aggregate projections from neurons which synthesize and communicate the monoamine neurotransmitter serotonin. [citation needed] These pathways are relevant to different psychiatric and neurological disorders. [1] [2] [3]
Serotonin (/ ˌ s ɛr ə ˈ t oʊ n ɪ n, ˌ s ɪər ə-/) [6] [7] [8] or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.Its biological function is complex, touching on diverse functions including mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vasoconstriction.
The mast cell, another granulocyte, is similar in appearance and function. Both cell types store histamine , a chemical that is secreted by the cells when stimulated. However, they arise from different branches of hematopoiesis , and mast cells usually do not circulate in the blood stream, but instead are located in connective tissue.
The 7 general serotonin receptor classes include a total of 14 known serotonin receptors. [9] The 15th receptor 5-HT 1P has been distinguished on the basis of functional and radioligand binding studies, its existence has never been definitely affirmed or refuted. [10] [11] The specific types have been characterized as follows: [12] [13] [14]
The 5-HT 3 receptor is expressed throughout the central and peripheral nervous systems and mediates a variety of physiological functions. [14] On a cellular level, it has been shown that postsynaptic 5-HT 3 receptors mediate fast excitatory synaptic transmission in rat neocortical interneurons, amygdala, and hippocampus, and in ferret visual ...