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The structure of the virus was first elucidated in 1958 using X-ray diffraction by a team at Birkbeck College led by Rosalind Franklin, [77] [78] showing the polio virus to have icosahedral symmetry. [79]
CD155 is a transmembrane protein with 3 extracellular immunoglobulin-like domains, D1-D3, where D1 is recognized by the virus. [8]Low resolution structures of CD155 complexed with poliovirus have been obtained using electron microscopy [9] while a high resolution structures of the ectodomain D1 and D2 of CD155 were solved by x-ray crystallography.
Poliomyelitis (/ ˌ p oʊ l i oʊ ˌ m aɪ ə ˈ l aɪ t ɪ s / POH-lee-oh-MY-ə-LY-tiss), commonly shortened to polio, is an infectious disease caused by the poliovirus. [1] Approximately 75% of cases are asymptomatic; [5] mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia.
During the early 1950s the UK was rocked by a series of polio epidemics, with as many as 8,000 people suffering paralytic poliomyelitis. The epidemics ended with the introduction of the oral polio ...
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The virus infects the throat and intestines, and can cause flu-like symptoms. Paralysis from the polio virus is rare. This year, polio cases have been detected in New York state, London and Jerusalem.
The polio vaccine has all but obliterated the illness that once killed thousands and paralyzed 15,000 people nationwide every year. ... is a distinctly contagious illness caused by a virus called ...
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