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Acanthosis nigricans is a medical sign characterised by brown-to-black, poorly defined, velvety hyperpigmentation of the skin. [1] It is usually found in body folds, [2] such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead and other areas.
Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis . Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair.
Melanoma is the most dangerous type of skin cancer; it develops from the melanin-producing cells known as melanocytes. [1] It typically occurs in the skin, but may rarely occur in the mouth, intestines, or eye (uveal melanoma). [1] [2] In women, melanomas most commonly occur on the legs; while in men, on the back. [2]
The cause of this condition is not clearly understood, but it is thought to result from a defect in embryologic development during the first 12 weeks of pregnancy. The defect is thought to cause a proliferation of melanocytes, the cells responsible for normal skin color. When melanocytes are produced at an extremely rapid rate, they form in ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 10 December 2024. "Skin pigmentation" redirects here. For animal skin pigmentation, see Biological pigment. Extended Coloured family from South Africa showing some spectrum of human skin coloration Human skin color ranges from the darkest brown to the lightest hues. Differences in skin color among ...
Small, itchy bumps: These may be red, white, or yellow and can appear around the hair follicles. They can be mistaken for acne . Pain or tenderness: The affected areas might be sore or painful to ...
[8] [12] In addition to flaky skin, seborrhoeic dermatitis can have areas of red, inflamed, and itchy skin that coincide with the area of skin flaking, but not all individuals have this symptom. [8] Seborrhoeic dermatitis of the scalp can appear similarly to dandruff. [11] When the scalp is affected, there can be associated temporary hair loss ...
The causes of the HAIR-AN syndrome are not fully understood. Some studies hypothesize that the HAIR-AN syndrome is caused by a combination of genetic and environmental factors. [7] [1] HAIR-AN is found in 1-3% women affected hyperandrogenism. [8] Other studies have proposed the SAHA syndrome as a cause of the HAIR-AN syndrome. [9]