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D-Phenylalanine (DPA, D-Phe), sold under the brand names Deprenon, Sabiben, and Sabiden, is an enantiomer of phenylalanine which is described as an antidepressant and is marketed as a prescription drug for medical use in Argentina. [1] [2] The medication has been marketed since at least the 1970s [3] and continued to be available by the 2000s. [1]
Phenylalanine (symbol Phe or F) [3] is an essential α-amino acid with the formula C 9 H 11 NO 2.It can be viewed as a benzyl group substituted for the methyl group of alanine, or a phenyl group in place of a terminal hydrogen of alanine.
Smart drink ingredients often include substances such as DL-phenylalanine or L-phenylalanine, L-tyrosine, choline (trimethylaminoethanol), pyroglutamic acid, B vitamins, glucuronolactone, and DMAE (dimethylaminoethanol). These amino acids were claimed to have positive or enhanced effects on alertness, stress resistance and energy levels.
DA-Phen is a conjugate of dopamine and the amino acid phenylalanine (Phe or Phen). [ 1 ] [ 2 ] It is slowly cleaved by brain enzymes ( t ½ = 460 minutes) to yield free dopamine but is also rapidly hydrolyzed in human blood plasma (t ½ = 28 minutes). [ 2 ]
Consumer Reports (CR), formerly Consumers Union (CU), is an American nonprofit consumer organization dedicated to independent product testing, investigative journalism, consumer-oriented research, public education, and consumer advocacy.
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