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Hormone replacement therapy (HRT), also known as menopausal hormone therapy (MHT), is for women with menopausal symptoms. It is based on the idea that the treatment may prevent discomfort caused by diminished circulating estrogen and progesterone hormones, or in the case of the surgically or prematurely menopausal, that it may prolong life and may reduce incidence of dementia. [1]
When preliminary results of the Women's Health Initiative clinical trial were published in 2003, they upended menopause care in the U.S. The study linked hormone therapy — a form of treatment ...
While a 2018 review found that taking progesterone and estrogen together can decrease this risk, [53] other reviews reported an increased risk of blood clots and pulmonary embolism when estrogen and progestogen were combined, particularly when treatment was started 10 years or more after menopause and when the women were older than 60 years.
It is used as endocrine therapy for women with estrogen or progesterone receptor-positive, stage 4 or recurrent metastatic breast cancer [7] and has demonstrated similar efficacy compared to tamoxifen as adjuvant treatment of breast cancer and in the treatment of metastatic breast cancer. [6]
A follow-up study to the Women’s Health Initiative finds that hormone replacement therapy is beneficial for women in menopause. The therapy can help relieve symptoms like hot flashes and night ...
Nice stressed that the symptoms women experience are real and treatments are available. Women with menopause symptoms ‘should be offered HRT as first-line treatment’ Skip to main content
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