Search results
Results from the WOW.Com Content Network
The urea cycle converts highly toxic ammonia to urea for excretion. [1] This cycle was the first metabolic cycle to be discovered by Hans Krebs and Kurt Henseleit in 1932, [2] [3] [4] five years before the discovery of the TCA cycle. The urea cycle was described in more detail later on by Ratner and Cohen.
For more information see urea cycle. Pages in category "Urea cycle" The following 21 pages are in this category, out of 21 total.
Mutations in the human ASL gene causes argininosuccinic aciduria, a rare autosomal recessive disorder, and results in deficiencies of the urea cycle. Argininosuccinate lyase is an intermediate enzyme in the urea synthesis pathway and its function is imperative to the continuation of the cycle.
L-Ornithine is one of the products of the action of the enzyme arginase on L-arginine, creating urea. Therefore, ornithine is a central part of the urea cycle, which allows for the disposal of excess nitrogen. Ornithine is recycled and, in a manner, is a catalyst. First, ammonia is converted into carbamoyl phosphate (H 2 NC(O)OPO 2−
The excretion of urea is called ureotelism. Land animals, mainly amphibians and mammals, convert ammonia into urea, a process which occurs in the liver and kidney. These animals are called ureotelic. [3] Urea is a less toxic compound than ammonia; two nitrogen atoms are eliminated through it and less water is needed for its excretion.
Main page; Contents; Current events; Random article; About Wikipedia; Contact us; Donate
Diagram of biochemical urea cycle. Uses only capital letters, no textual description. 16:16, 5 February 2006: 800 × 600 (80 KB) Ayacop: Diagram of biochemical urea cycle. Uses only capital letters, no textual description. 16:09, 5 February 2006: 800 × 600 (80 KB) Ayacop: Diagram of biochemical urea cycle. Uses only capital letters, no textual ...
Citrulline is a metabolic intermediate within the urea cycle, which is the pathway by which mammals excrete ammonia by converting it into urea. Citrulline is also produced as a byproduct of the enzymatic production of nitric oxide from the amino acid arginine, catalyzed by nitric oxide synthase.