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Propentofylline was studied as a possible treatment for Alzheimer's disease and multi-infarct dementia, [1] [4] and has been studied, to a lesser extent, as a possible adjunct in the treatment of ischemic stroke, due to its vasodilating properties. [5] [6] Propentofylline is in use as a veterinary medicine in older dogs. [7]
Canine cognitive dysfunction (CCD) is a disease prevalent in dogs that exhibit symptoms of dementia or Alzheimer's disease shown in humans. [1] CCD creates pathological changes in the brain that slow the mental functioning of dogs resulting in loss of memory, motor function, and learned behaviors from training early in life.
pentoxyfylline – xanthine derivative used in as an antiinflammatory drug and in the prevention of endotoxemia; pergolide – dopamine receptor agonist used for the treatment of pituitary pars intermedia dysfunction in horses; phenobarbital – anti-convulsant used for seizures; phenylbutazone – nonsteroidal anti-inflammatory drug (NSAID)
Last month, new research was presented at the Alzheimer’s Association International Conference in Philadelphia that is big news when it comes to dementia prevention. The findings are part of a ...
The AKC reports that one study found that 28% of dogs between 11 and 12 years of age have at least one sign of dog dementia, and that increased to 68% in dogs over 15 years of age.
A recent study found that a class of medications called SGLT-2 inhibitors—which does not include Ozempic or similar drugs like Zepbound—significantly lowered the risk of dementia in people ...
Deracoxib is a coxib class nonsteroidal anti-inflammatory drug (NSAID). [3] Like other NSAIDs, its effects are caused by inhibition of cyclooxygenase (COX) enzymes. [7] At the doses used to treat dogs, deracoxib causes greater inhibition of COX-2 than of COX-1, [3] but at doses twice those recommended for use in dogs, deracoxib significantly inhibits COX-1 as well.
Dementia prevention is a critical area of research, as experts want to understand what people can do to decrease dementia risk. A recent study found that more than 5 years of taking medications ...
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