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This image is a derivative work of the following images: File:DNA_replication_en.svg licensed with PD-user . 2009-06-01T14:09:19Z Bibi Saint-Pol 691x336 (113021 Bytes) {{Information |Description= {{en|DNA replication or DNA synthesis is the process of copying a double-stranded DNA molecule.
Printable version; Page information; ... The factual accuracy of this diagram or the file name is disputed. ... DNA replication or DNA synthesis is the process of ...
Printable version; Page information; Get shortened URL ... DNA diagram during replication. Date: 2 July 2019: Source: Own work: ... DNA replication fork made to ...
A-level Biology/Biology Foundation/protein structure and function; An Introduction to Molecular Biology/DNA the unit of life; An Introduction to Molecular Biology/Replication of DNA and its repair; Usage on en.wikiversity.org Introduction to Genetics; Template:Annotated image/doc/Samples; Template:Annotated image/testcases; Usage on es ...
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Eukaryotes initiate DNA replication at multiple points in the chromosome, so replication forks meet and terminate at many points in the chromosome. Because eukaryotes have linear chromosomes, DNA replication is unable to reach the very end of the chromosomes. Due to this problem, DNA is lost in each replication cycle from the end of the chromosome.
During DNA replication, the replisome will unwind the parental duplex DNA into a two single-stranded DNA template replication fork in a 5' to 3' direction. The leading strand is the template strand that is being replicated in the same direction as the movement of the replication fork.
The combination of template DNA and primer RNA is referred to as 'A-form DNA' and it is thought that clamp loading replication proteins (helical heteropentamers) want to associate with A-form DNA because of its shape (the structure of the major/minor groove) and chemistry (patterns of hydrogen bond donors and acceptors).