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In 1989, in a 4- to 6-year follow-up study of 30 inpatient people who used benzodiazepines non-medically, Neuropsychological function was found to be permanently affected in some people with long-term high dose non-medical use of benzodiazepines. Brain damage similar to alcoholic brain damage was observed.
Benzodiazepines are one of the most highly prescribed classes of drugs, [7] and they are commonly used in self-poisoning. [8] [9] Over 10 years in the United Kingdom, 1512 fatal poisonings have been attributed to benzodiazepines with or without alcohol. [10] Temazepam was shown to be more toxic than the majority of benzodiazepines.
A 1985 study found that triazolam and temazepam maintained higher rates of self-injection in both human and animal subjects compared to a variety of other benzodiazepines (others examined: diazepam, lorazepam, oxazepam, flurazepam, alprazolam, chlordiazepoxide, clonazepam, nitrazepam, flunitrazepam, bromazepam, and clorazepate). [7]
The source for the data below is the OECD Health Statistics 2018, released by the OECD in June 2018 and updated on 8 November 2018. [1]The unit of measurement used by the OECD is defined daily dose (DDD), defined as "the assumed average maintenance dose per day for a drug used on its main indication in adults". [2]
“That’s nearly 17,000 people dying from prescription opiate overdoses every year. And more than 400,000 go to an emergency room for that reason.” Clinics that dispensed painkillers proliferated with only the loosest of safeguards, until a recent coordinated federal-state crackdown crushed many of the so-called “pill mills.”
Due to the serious concerns of addiction, national governments were recommended to urgently seek to raise knowledge via training about the addictive nature of benzodiazepines and appropriate prescribing of benzodiazepines. [81] A six-year study on 51 Vietnam veterans who had a substance use disorder related mainly to stimulants (11 people ...
Cocaine contributed to roughly 15,000 overdose deaths, while methamphetamine and benzodiazepines each contributed to roughly 11,000 deaths. [74] Of note, the mortality from each individual drug listed above cannot be summed because many of these deaths involved combinations of drugs, such as overdosing on a combination of cocaine and an opioid ...
Of people who come into and go out of the federal workforce each year, there were hundreds of thousands of civilian employees (not counting postal workers) – about 250,000 to just over 300,000 ...