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  2. Endochondral ossification - Wikipedia

    en.wikipedia.org/wiki/Endochondral_ossification

    This newly formed bone can be called "periosteal bone" as it originates from the transformed periosteum. However, considering its developmental pathway, it could be classified as "intramembranous bone". [8] After the formation of the periosteum, chondrocytes in the primary center of ossification begin to grow (hypertrophy).

  3. Fibrodysplasia ossificans progressiva - Wikipedia

    en.wikipedia.org/wiki/Fibrodysplasia_ossificans...

    Fibrodysplasia ossificans progressiva (/ ˌ f aɪ b r oʊ d ɪ ˈ s p l eɪ ʒ (i) ə ɒ ˈ s ɪ f ɪ k æ n z p r ə ˈ ɡ r ɛ s ɪ v ə /; [1] abbr. FOP), also called Münchmeyer disease or formerly myositis ossificans progressiva, is an extremely rare connective tissue disease in which fibrous connective tissue such as muscle, tendons, and ligaments turn into bone tissue (ossification).

  4. Ossification - Wikipedia

    en.wikipedia.org/wiki/Ossification

    It is synonymous with bone tissue formation. [1] There are two processes resulting in the formation of normal, healthy bone tissue : [ 2 ] Intramembranous ossification is the direct laying down of bone into the primitive connective tissue ( mesenchyme ), while endochondral ossification involves cartilage as a precursor.

  5. Osteochondrosis - Wikipedia

    en.wikipedia.org/wiki/Osteochondrosis

    The term osteochondrosis has been used to describe a wide range of lesions among different species. There are different types of the prognosis: latens, which is a lesion restricted to epiphyseal cartilage, manifesta, a lesion paired with a delay in endochondral ossification, and dissecans which is a cleft formation in the articular cartilage. [1]

  6. Chondrocyte - Wikipedia

    en.wikipedia.org/wiki/Chondrocyte

    Endochondral ossification is the process by which most vertebrate axial skeletons form into hardened bones from cartilage. This process begins with a cartilage anlage where chondrocyte cells will congregate and start their maturation process. Once the chondrocytes have fully matured at the desired rate, the cartilage tissue will harden into ...

  7. Cleidocranial dysostosis - Wikipedia

    en.wikipedia.org/wiki/Cleidocranial_dysostosis

    It is due to a defect in the RUNX2 gene which is involved in bone formation. [1] Diagnosis is suspected based on symptoms and X-rays with confirmation by genetic testing . [ 4 ] Other conditions that can produce similar symptoms include mandibuloacral dysplasia , pyknodysostosis , osteogenesis imperfecta , and Hajdu-Cheney syndrome .

  8. Osteochondrodysplasia - Wikipedia

    en.wikipedia.org/wiki/Osteochondrodysplasia

    An osteochondrodysplasia, [note 1] or skeletal dysplasia, is a disorder of the development of bone and cartilage. [1] Osteochondrodysplasias are rare diseases.About 1 in 5,000 babies are born with some type of skeletal dysplasia. [2]

  9. Achondroplasia - Wikipedia

    en.wikipedia.org/wiki/Achondroplasia

    Achondroplasia results in impaired endochondral bone growth (bone growth within cartilage). [7] The disorder has an autosomal dominant mode of inheritance, meaning only one mutated copy of the gene is required for the condition to occur. [ 8 ]