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Very common adverse effects of olanzapine, occurring more than 10%, include: Weight gain (dose-dependent). Weight gain of over 7% of a person's initial body weight prior to treatment is in this category of very common too with some estimates of its incidence putting it at around 40.6%.
Although antagonistic effects of olanzapine at 5-HT 2C alone are not associated with weight gain, olanzapine antagonism at histaminergic H 1, and muscarinic M 3 receptors have been implicated in weight gain. [92] [103] [104] The mode of action of olanzapine's antipsychotic activity is unknown. It may involve antagonism of dopamine and serotonin ...
Weight gain [18] There has been a study that suggests antipsychotics are associated with possible cortical reconfiguration and gray matter loss, [19] but correlational data also suggests patients who consume antipsychotics, like people with schizophrenia, tend to engage in unhealthy habits like smoking which may exacerbate gray matter loss. [20]
The authors noted an apparent superior efficacy of olanzapine to the other drugs in terms of reduction in psychopathology and rate of hospitalizations, but olanzapine was associated with relatively severe metabolic effects such as a major weight gain problem (averaging 9.4 lbs over 18 months) and increases in glucose, cholesterol, and ...
Side effects vary depending on the type of medication used. Some common side effects of bipolar medications include weight gain and fatigue or drowsiness. These side effects can usually be managed ...
Pooled data across five clinical trials showed that the average weight loss after six months on Xenical was 12.4 pounds and after a year of treatment it was 13.4 pounds.
1. Eat Nutritious Foods. Your eating habits might be a little different during the winter, and in general, healthy eating can be harder. To avoid weight gain, aim for a balanced diet of nutritious ...
Weight gain (particularly prominent with clozapine, olanzapine, quetiapine and zotepine, [38] can be counteracted by starting the drug with metformin [125] [126]) Anticholinergic side-effects (common for olanzapine, clozapine; less likely on risperidone [127]) such as: Blurred vision; Constipation; Dry mouth (although hypersalivation may also ...
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