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Weight gain; Uncontrolled movement such as restlessness, tremor muscle stiffness [7] References This page was last edited on 12 April 2024, at 14:13 (UTC). Text is ...
Unlike other antipsychotics, aripiprazole is a high-efficacy partial agonist of the postsynaptic 5-HT 2C receptor (intrinsic activity = 82%) this property may underlie the minimal weight gain seen in the course of therapy, however if used while taking antidepressants it will become a functional antagonist and increase weight gain. [91]
Adverse effects vary among the various agents in this class of medications, but common effects include: dry mouth, muscle stiffness, muscle cramping, tremors, EPS and weight gain. EPS refers to a cluster of symptoms consisting of akathisia, parkinsonism, and dystonia.
Maintenance therapy with antipsychotic drugs is clearly superior to placebo in preventing relapse but is associated with weight gain, movement disorders, and high dropout rates. [40] A 3-year trial following persons receiving maintenance therapy after an acute psychotic episode found that 33% obtained long-lasting symptom reduction, 13% ...
The two atypical antipsychotics with trials showing that had a low incidence of weight gain in large meta-analysis were lurasidone and aripiprazole. [69] In a meta-analysis of 18 antipsychotics, olanzapine and clozapine exhibited the worst metabolic parameters and aripiprazole, brexpiprazole, cariprazine, lurasidone, and ziprasidone the most ...
“Just as much as the GLP-1s are a diabetes drug and a weight loss medicine, they are brain drugs, too,” says Rekha Kumar, MD, an endocrinologist at New York-Presbyterian and Weill Cornell ...
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But significant weight loss will generally take longer. A Novo Nordisk-funded 2021 study looked at almost 2,000 adults with excess body weight or obesity without diabetes. Participants took once ...