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The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts.
What is hip pain? Your hip joint supports basic functions of balance and movement in the body, such as holding up body weight and enabling upper leg movement. It’s a ball-and-socket joint that ...
Overview. Sudden hip pain, shooting pain, a dull ache — all can be symptoms of issues involving your hip. The hip joint contains the ball of the thigh bone and the pelvis socket.
Age. The risk of most causes of joint pain increases with age. This may be due to increased wear and stress on joints over time and a higher likelihood of other underlying medical conditions ...
Snapping hip, a condition caused by iliotibial band snap, iliopsoas tendon snap, and hip labral tear, usually only in one hip; may be accompanied by an audible "snap" when the hip joint is moved; Paget's disease, enlarged or deformed bones of the hip, a genetic disorder; pain is usually in both hips simultaneously
The protein kinase domain is 330 amino acids long and is located near the N-terminus of the protein. [ 23 ] [ 24 ] In addition to its kinase domain, HIPK2 has two nuclear localization signals, [ 25 ] a SUMO interaction motif, [ 25 ] an auto-inhibitory domain [ 23 ] a transcriptional co-repression domain, [ 13 ] and several interaction domains ...
Coxalgia is a symptom of underlying hip joint pathology and must be examined and referred as the symptoms of pain and reduced mobility will increase and worsen, leading to chronic pain states. Coxalgia may be due to trauma, dysplasia and abnormal growth, degeneration, osteo-deficiencies of B12 or folate or metastasising cancer.
"Joint pain, like any other pain in the body, is a signal that something may not be working properly in our musculoskeletal system," says Dr. Jeffrey Zarin, MD, an orthopedic surgeon specializing ...
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