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  2. RNA world - Wikipedia

    en.wikipedia.org/wiki/RNA_world

    The RNA world hypothesis places RNA at center-stage when life originated. The RNA world hypothesis is supported by the observations that ribosomes are ribozymes: [120] [121] the catalytic site is composed of RNA, and proteins hold no major structural role and are of peripheral functional importance. This was confirmed with the deciphering of ...

  3. Woese's dogma - Wikipedia

    en.wikipedia.org/wiki/Woese's_dogma

    Woese's dogma is a principle of evolutionary biology first put forth by biophysicist Carl Woese in 1977. It states that the evolution of ribosomal RNA was a necessary precursor to the evolution of modern life forms. [1]

  4. Last universal common ancestor - Wikipedia

    en.wikipedia.org/wiki/Last_universal_common_ancestor

    If the genetic code was based on dual-stranded DNA, it was expressed by copying the information to single-stranded RNA. The RNA was produced by a DNA-dependent RNA polymerase using nucleotides similar to those of DNA. [15] It had multiple DNA-binding proteins, such as histone-fold proteins. [21] The genetic code was expressed into proteins.

  5. First universal common ancestor - Wikipedia

    en.wikipedia.org/wiki/First_universal_common...

    FUCA was generated without genetic code, from the ribosome, [1] itself a system evolved from the maturation of a ribonucleoprotein machinery. [4] FUCA appeared when a proto-peptidyl transferase center started to first emerge, when RNA world replicators started to be capable to catalyze the bonding of amino acids into oligopeptides. [1]

  6. Hypothetical types of biochemistry - Wikipedia

    en.wikipedia.org/wiki/Hypothetical_types_of...

    The genetic code may have evolved during the transition from the RNA world to a protein world. [86] The Alanine World Hypothesis postulates that the evolution of the genetic code (the so-called GC phase [87]) started with only four basic amino acids: alanine, glycine, proline and ornithine (now arginine). [88]

  7. Evolution of cells - Wikipedia

    en.wikipedia.org/wiki/Evolution_of_cells

    The nearly universal genetic code preserves some evidence for the RNA world. For instance, recent studies of transfer RNAs, the enzymes that charge them with amino acids (the first step in protein synthesis) and the way these components recognize and exploit the genetic code, have been used to suggest that the universal genetic code emerged ...

  8. Today’s NYT ‘Strands’ Hints, Spangram and Answers for ...

    www.aol.com/today-nyt-strands-hints-spangram...

    We'll cover exactly how to play Strands, hints for today's spangram and all of the answers for Strands #284 on Thursday, December 12. Related: 16 Games Like Wordle To Give You Your Word Game Fix ...

  9. Ligase ribozyme - Wikipedia

    en.wikipedia.org/wiki/Ligase_ribozyme

    The RNA Ligase ribozyme was the first of several types of synthetic ribozymes produced by in vitro evolution and selection techniques. They are an important class of ribozymes because they catalyze the assembly of RNA fragments into phosphodiester RNA polymers, a reaction required of all extant nucleic acid polymerases and thought to be ...