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The website provides a free online collection of multimedia including educational games, videos, images, and lesson plans, with a focus on game-based learning. Spongelab.com is a web-based teaching platform that allows educators to combine science, discovery learning tools and technology to create a visually engaging interactive whole. [ 1 ]
In Lesson 3, the user is in the mitochondrion, where they have to convert the sugar into energy by playing the Glycolysis, Citric Acid Cycle, and Electron Transport Chain games. Finally, in Lesson 4, the user is in the nucleus, where they use the energy to build proteins by playing the Transcription and Translation games. Once a user completes ...
"The metabolic pathway of glycolysis converts glucose to pyruvate via a series of intermediate metabolites. Each chemical modification (red box) is performed by a different enzyme. Steps 1 and 3 consume ATP (blue) and steps 7 and 10 produce ATP (yellow). Since steps 6-10 occur twice per glucose molecule, this leads to a net production of energy."
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d -Glucose + 2 [NAD] + + 2 [ADP] + 2 [P] i 2 × Pyruvate 2 × + 2 [NADH] + 2 H + + 2 [ATP] + 2 H 2 O Glycolysis pathway overview The use of symbols in this equation makes it appear unbalanced with respect to oxygen atoms, hydrogen atoms, and charges. Atom balance is maintained by the two phosphate (P i) groups: Each exists in the form of a hydrogen phosphate anion, dissociating to contribute ...
Anaerobic glycolysis exclusively uses glucose (and glycogen) as a fuel in the absence of oxygen, or more specifically, when ATP is needed at rates that exceed those provided by aerobic metabolism. The consequence of such rapid glucose breakdown is the formation of lactic acid (or more appropriately, its conjugate base lactate at biological pH ...
Using an Alzheimer’s mouse model, they found that blocking the enzyme, called indoleamine-2,3-dioxygenase 1, or IDO1, helped preserve memory and cognition in the early stages of the disease.
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