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2-Octyl cyanoacrylate is a cyanoacrylate ester typically used as a wound closure adhesive (under the brand name Dermabond). [1] It is closely related to octyl cyanoacrylate . The use of 2-octyl cyanoacrylate was approved in 1998; offered as an alternative to stitches, sutures, and or adhesive strips.
Octyl cyanoacrylate (OCA), a cyanoacrylate ester, is an octyl ester of 2-cyano-2-propenoic acid. It is a clear colorless liquid with a sharp, irritating odor. Its chief use is as the main component of medical cyanoacrylate glues. In medical and veterinary applications, OCA, n-butyl cyanoacrylate (n-BCA) and isobutyl cyanoacrylate (ICA
The compound 2-octyl cyanoacrylate degrades much more slowly due to its longer organic backbone (series of covalently bonded carbon molecules) and the adhesive does not reach the threshold of tissue toxicity. Due to the toxicity issues of ethyl cyanoacrylate, the use of 2-octyl cyanoacrylate for sutures is preferred. [33]
There are three cyanoacrylate compounds currently available as topical skin adhesives. 2-Octyl cyanoacrylate is marketed as Dermabond, SurgiSeal, and more recently LiquiBand Exceed. n-Butyl cyanoacrylate is marketed as Histoacryl, Indermil, GluStitch, GluSeal, PeriAcryl, and LiquiBand. The compound ethyl 2-cyanoacrylate is available as Epiglu. [3]
Liquid bandage is a topical skin treatment for minor wounds which binds to the skin to form a protective polymeric layer that keeps dirt and germs out and moisture in. [1] It can be directly applied to the wound after removing debris.
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Wikidata item; Appearance. move to sidebar hide ... Octyl cyanoacrylate; 2-Octyl cyanoacrylate; Psi-DOM This page was last edited on 21 November 2023, at 01 ...
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