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According to a study by Eagle et al., patients 50–59 years old have an operative mortality rate of 1.8%, while patients older than 80 have a rate of 8.3%. [33] Other factors that increase mortality are being female, re-operation, dysfunction of the left ventricle, and left main disease. [33]
The advancement of cardiac surgery and cardiopulmonary bypass techniques has greatly reduced the mortality rates of these procedures. For instance, repairs of congenital heart defects are currently estimated to have 4–6% mortality rates. [35] [36] A major concern with cardiac surgery is neurological damage.
Although several studies showed benefits from this surgery, studies at the Cleveland Clinic concluded that this procedure was associated with a high early and late failure rate. At 3 years only 26 percent were event-free and survival rate was only 60 percent. [2]
Long-term survival rates for children with single ventricle physiology are improving as medical and surgical advancements continue. In the major SVR trial (Single Ventricle Reconstruction) the transplant-free survival rate was only 54-59% amongst patients who underwent the Norwood procedure. [ 32 ]
It is estimated in 2018 there was an 85% for a survival rate of thirty years following a Fontan procedure and there are approximately 50,000 to 70,000 people in the world with Fontan circulation. [23] It is approximated that 40% of people with Fontan circulation are ≥18 years of age. [22]
Approximately 3,500 heart transplants are performed each year worldwide, more than half of which are in the US. [2] Post-operative survival periods average 15 years. [3] Heart transplantation is not considered to be a cure for heart disease; rather it is a life-saving treatment intended to improve the quality and duration of life for a ...
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