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Hox genes, a subset of homeobox genes, are a group of related genes that specify regions of the body plan of an embryo along the head-tail axis of animals. Hox proteins encode and specify the characteristics of 'position', ensuring that the correct structures form in the correct places of the body.
[10] [11] Morphogens in Drosophila include decapentaplegic and hedgehog. [10] During development, retinoic acid, a metabolite of vitamin A, is used to stimulate the growth of the posterior end of the organism. [12] Retinoic acid binds to retinoic acid receptors that acts as transcription factors to regulate the expression of Hox genes. Exposure ...
15426 Ensembl ENSG00000037965 n/a UniProt P31273 P09025 RefSeq (mRNA) NM_022658 NM_010466 RefSeq (protein) NP_073149 NP_034596 Location (UCSC) Chr 12: 54.01 – 54.01 Mb n/a PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-C8 is a protein that in humans is encoded by the HOXC8 gene. Function This gene belongs to the homeobox family of genes. The homeobox genes encode ...
3211 15407 Ensembl ENSG00000120094 ENSMUSG00000018973 UniProt P14653 P17919 RefSeq (mRNA) NM_002144 NM_008266 RefSeq (protein) NP_002135 NP_032292 Location (UCSC) Chr 17: 48.53 – 48.53 Mb Chr 11: 96.26 – 96.26 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-B1 is a protein that in humans is encoded by the HOXB1 gene. Function This gene belongs to the homeobox ...
Drosophila is known to use the polycomb and trithorax complexes to maintain the expression of Hox genes after the down-regulation of the pair-rule and gap genes that occurs during larval development. Polycomb-group proteins can silence the Hox genes by modulation of chromatin structure.
15394 Ensembl ENSG00000105991 ENSMUSG00000029844 UniProt P49639 P09022 RefSeq (mRNA) NM_153620 NM_005522 NM_010449 NM_001311118 RefSeq (protein) NP_005513 NP_705873 n/a Location (UCSC) Chr 7: 27.09 – 27.1 Mb Chr 6: 52.13 – 52.14 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-A1 is a protein that in humans is encoded by the HOXA1 gene. Gene Two transcript ...
3200 15400 Ensembl ENSG00000105997 ENSMUSG00000079560 UniProt O43365 P02831 RefSeq (mRNA) NM_030661 NM_153631 NM_153632 NM_010452 RefSeq (protein) NP_109377 NP_705895 NP_034582 Location (UCSC) Chr 7: 27.11 – 27.15 Mb Chr 6: 52.15 – 52.19 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-A3 is a protein that in humans is encoded by the HOXA3 gene. Function In ...
15424 Ensembl ENSG00000172789 ENSMUSG00000022485 UniProt Q00444 P32043 RefSeq (mRNA) NM_018953 NM_175730 RefSeq (protein) NP_061826 NP_783857 Location (UCSC) Chr 12: 54.03 – 54.04 Mb Chr 15: 102.88 – 102.93 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-C5 is a protein that in humans is encoded by the HOXC5 gene. Function This gene belongs to the homeobox ...