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Sensitivity to acute thermal stimulation is the most common test used in live species pain research. [2] The behavioral reflex evoked by noxious heat stimuli is a relatively good predictor of pain sensitivity and its reduction through various analgesics .
A computer mouse with the most common features: two buttons (left and right) and a scroll wheel (which can also function as a button when pressed inwards) A typical wireless computer mouse. A computer mouse (plural mice, also mouses) [nb 1] is a hand-held pointing device that detects two-dimensional motion relative to a surface
Assay sensitivity is a property of a clinical trial defined as the ability of a trial to distinguish an effective treatment from a less effective or ineffective intervention. [1] Without assay sensitivity, a trial is not internally valid and is not capable of comparing the efficacy of two interventions.
The hot plate test is a test of the pain response in animals, similar to the tail flick test. Both hot plate and tail-flick methods are used generally for centrally acting analgesic, [ 1 ] while peripherally acting drugs are ineffective in these tests but sensitive to acetic acid-induced writhing test.
The typical detection efficiency of preclinical SPECT scanner lies within a 0.1-0.2% (1000-2000 cps/MBq) range, which is more than tenfold higher than the average sensitivity of clinical scanners. [17] At the same time, dedicated high-sensitivity collimators can allow >1% detection efficiency and maintain sub-mm image resolution. [18]
The wheel was designed to test nerve reactions (sensitivity) as it rolled systematically across the skin. [1] A Wartenberg wheel is generally made of stainless steel with a handle of approximately 18 centimetres (7 in) in length. The wheel, which has evenly spaced radiating sharp pins, rotates as it is rolled across the flesh.
In medical diagnosis, test sensitivity is the ability of a test to correctly identify those with the disease (true positive rate), whereas test specificity is the ability of the test to correctly identify those without the disease (true negative rate). If 100 patients known to have a disease were tested, and 43 test positive, then the test has ...
High sensitive troponin I has been proven to have superior clinical performance versus high sensitivity troponin T in patients with renal impairment [17] and skeletal muscle disease. [18] [19] It is also not affected by diurnal rhythm, which is important when the test is used as a screening tool for CVD. [20]
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