Search results
Results from the WOW.Com Content Network
These oxidative molecules can cause oxidative brain damage. Iron that is bound to ferritin in nonreactive. [1] Fenton Reaction (1) Fe 2+ + H 2 O 2 → Fe 3+ + HO• + OH − (2) Fe 3+ + H 2 O 2 → Fe 2+ + HOO• + H + The ferritin protein is made up of heavy chain (H) and light chain (L) subunits. In neuroferritinopathy, the gene encoding the ...
However ferritin levels may be elevated due to a variety of other causes including obesity, infection, inflammation (as an acute phase protein), chronic alcohol intake, liver disease, kidney disease, and cancer. [7] [32] [33] In males and postmenopausal females, normal range of serum ferritin is between 12 and 300 ng/mL (670 pmol/L) .
The ferritin levels measured usually have a direct correlation with the total amount of iron stored in the body. However, ferritin levels may be artificially high in cases of anemia of chronic disease, where ferritin is elevated in its capacity as an inflammatory acute phase protein and not as a marker for iron overload. [citation needed]
More ferritin is produced to suppress oxidative cell damage, although the amount of ferritin that cells can accumulate is limited. [ 12 ] Hemochromatosis type 4B is characterized by abnormal iron release from macrophages and enterocytes because the mutant ferroportin is resistant to the hepcidin protein, which serves a regulatory function in ...
Camp says it can be a cause for scalp scabs, and it also causes “flaky, pink patches on the scalp, eyebrows, ears, around the nose, and beard area.” Other symptoms include itchiness, rash, and ...
Similarly, lichen sclerosus is a patchy white rash that causes intense itching in your genital area (though it can appear on other parts of the body, too). People in their 40s and 50s are most ...
Generalized itch, or itching across the whole body, can be a symptom of a dermatological disorder or an underlying systemic problem. [13] Some systemic diseases can that cause generalized itch include diabetes, hypothyroidism, kidney diseases and liver diseases. [14] [13] It is usually treated with systemic agents instead of topical agents. [15]
What does it mean to have a high ferratin level of 430? tcr It depends completely on the circumstances under which the test was performed. If it was done while inflammation was present, it may be part of the acute phase response. There are many other causes for hyperferritinaemia, e.g. haemochromatosis is marked by high ferritin.