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  2. DESeq2 - Wikipedia

    en.wikipedia.org/wiki/DESeq2

    By incorporating the negative binomial distribution, DESeq2 accurately models the dispersion of gene expression counts and provides more reliable estimates of differential expression. DESeq2 also offers an adaptive shrinkage procedure, known as the "apeglm" method, which is particularly useful when dealing with small sample sizes. [ 6 ]

  3. List of RNA-Seq bioinformatics tools - Wikipedia

    en.wikipedia.org/wiki/List_of_RNA-Seq...

    Using DESeq2 as a framework, DEvis provides a wide variety of tools for data manipulation, visualization, and project management. DEXSeq is Bioconductor package that finds differential differential exon usage based on RNA-Seq exon counts between samples. DEXSeq employs negative binomial distribution, provides options to visualization and ...

  4. RNA-Seq - Wikipedia

    en.wikipedia.org/wiki/RNA-Seq

    Methods: Most tools use regression or non-parametric statistics to identify differentially expressed genes, and are either based on read counts mapped to a reference genome (DESeq2, limma, edgeR) or based on read counts derived from alignment-free quantification (sleuth, [106] Cuffdiff, [107] Ballgown [108]). [109]

  5. Man who attacked, then rescued, ex-wife hoped to be her hero

    www.aol.com/man-attacked-then-rescued-ex...

    On Aug. 4, 2021, Rod pleaded guilty to a total of 14 counts related to Morgan's attack and the photos found on his phone. Sgt. Robert Haugh: He agreed to serve 25 years on a 70-year sentence.

  6. Woman who zipped boyfriend in suitcase, suffocating him ... - AOL

    www.aol.com/woman-zipped-boyfriend-suitcase...

    A Florida woman who said she was playing a game with her boyfriend when she zipped him up in a suitcase and left him to die has been sentenced to life in prison.

  7. Women speak of shocking sexual violence amid Sudan's raging ...

    www.aol.com/news/women-speak-shocking-sexual...

    A Sudanese woman identified only as Hania, 18, told Human Rights Watch she was pregnant in February 2024 when RSF fighters burst into her home in Habila, South Kordofan state, and abducted her ...

  8. Single-cell transcriptomics - Wikipedia

    en.wikipedia.org/wiki/Single-cell_transcriptomics

    Insights based on single-cell data analysis assume that the input is a matrix of normalised gene expression counts, generated by the approaches outlined above, and can provide opportunities that are not obtainable by bulk. Three main insights provided: [18] Identification and characterization of cell types and their spatial organisation in time

  9. Transcriptomics technologies - Wikipedia

    en.wikipedia.org/wiki/Transcriptomics_technologies

    Once quantitative counts of each transcript are available, differential gene expression is measured by normalising, modelling, and statistically analysing the data. [108] Most tools will read a table of genes and read counts as their input, but some programs, such as cuffdiff, will accept binary alignment map format read alignments as input.