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The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. It does not include any risks conferred by pharmaceutical agents or their metabolites in breast milk. Every drug has specific information listed in its product literature.
The placebo-subtracted mean weight losses were 4.5%, 9.2% and 10.6% in the 0.25 mg, 0.5 mg and 1 mg dose groups, respectively. The weight loss seen in the Phase IIB trial was approximately double that produced by medications that had been approved (as of 2008) by the US Food and Drug Administration (FDA) for the treatment of obesity. [19]
The US Food and Drug Administration (FDA) considers it to be a first-in-class medication. [20] [21] It was approved by the FDA for weight loss in November 2023. [16] [22] In November 2023, the UK Medicines and Healthcare products Regulatory Agency revised the indication for tirzepatide to include treatment for weight loss.
[50] [56] Combined birth control pills containing drospirenone are approved for the treatment of PMDD and may be particularly beneficial due to the antimineralocorticoid activity of drospirenone. [ 50 ] [ 57 ] [ 58 ] Studies on the influence of hormonal birth control on mood in women with existing mood disorders or polycystic ovary syndrome are ...
Vilazodone was approved for medical use in the United States in 2011 [1] and in Canada in 2018. [8] In 2019, it was the 334th most commonly prescribed medication in the United States, with more than 900 thousand prescriptions. [9] The drug lost patent protection in June 2022 for adults and in July 2023 for pediatrics. [10]
EE/CPA is used as a combined birth control pill to prevent ovulation and pregnancy in women. [2] It is also approved and used to treat androgen-dependent conditions in women such as acne , seborrhea , hirsutism , female pattern hair loss , and hyperandrogenism due to polycystic ovary syndrome .
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In the US, the drug label contains warnings for increased heart rate, suicidal behavior and ideation, glaucoma, mood and sleep disorders, creatinine elevation, and metabolic acidosis. Some of these warnings are based on historical observations in epilepsy patients taking topiramate.