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- In tendon development first signals are detectable as early as E9.5, [7] but upregulated from E14.5 onwards, marking the differentiated stage of tendon progenitors. [ 18 ] - Mouse periodontal ligaments demonstrated tenomodulin protein expression at 3 and 4 weeks postnatal, a time period corresponding to molar eruptive and post-eruptive phases ...
DNA repair protein XRCC4 (hXRCC4) also known as X-ray repair cross-complementing protein 4 is a protein that in humans is encoded by the XRCC4 gene. XRCC4 is also expressed in many other animals, fungi and plants. [5] hXRCC4 is one of several core proteins involved in the non-homologous end joining (NHEJ) pathway to repair DNA double strand ...
217716 Ensembl ENSG00000119684 ENSMUSG00000021245 UniProt Q9UHC1 n/a RefSeq (mRNA) NM_001040108 NM_014381 NM_145446 NM_175337 NM_001304475 RefSeq (protein) NP_001035197 NP_055196 n/a Location (UCSC) Chr 14: 75.01 – 75.05 Mb Chr 12: 85.28 – 85.32 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse DNA mismatch repair protein Mlh3 is a protein that in humans is encoded by the MLH3 gene ...
Tendon cells, or tenocytes, are elongated fibroblast type cells. The cytoplasm is stretched between the collagen fibres of the tendon. They have a central cell nucleus with a prominent nucleolus. Tendon cells have a well-developed rough endoplasmic reticulum and they are responsible for synthesis and turnover of tendon fibres and ground substance.
Sirtuin 6 (SIRT6 or Sirt6) is a stress responsive protein deacetylase and mono-ADP ribosyltransferase enzyme encoded by the SIRT6 gene. [5] [6] [7] In laboratory research, SIRT6 appears to function in multiple molecular pathways related to aging, including DNA repair, telomere maintenance, glycolysis and inflammation. [5]
545 245000 Ensembl ENSG00000175054 ENSMUSG00000032409 UniProt Q13535 Q9JKK8 RefSeq (mRNA) NM_001184 NM_001354579 NM_019864 RefSeq (protein) NP_001175 NP_001341508 n/a Location (UCSC) Chr 3: 142.45 – 142.58 Mb Chr 9: 95.74 – 95.83 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Serine/threonine-protein kinase ATR, also known as ataxia telangiectasia and Rad3-related protein (ATR ...
Nse1-Nse3-Nse4 subunits bridge the heads of the Smc5 and Smc6 proteins and allow the complex to bind DNA. Nse5 and Nse6 form a sub-complex which localizes to the head of the SMC5/6 complex in the budding yeast Saccharomyces cerevisiae, and to the hinges of the SMC5/6 complex in the fission yeast Schizosaccharomyces pombe.
235626 Ensembl ENSG00000181555 ENSMUSG00000044791 UniProt Q9BYW2 E9Q5F9 RefSeq (mRNA) NM_012271 NM_014159 NM_001349370 NM_001081340 RefSeq (protein) NP_054878 NP_001336299 NP_001074809 Location (UCSC) Chr 3: 47.02 – 47.16 Mb Chr 9: 110.53 – 110.62 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse SET domain containing 2 is an enzyme that in humans is encoded by the SETD2 gene ...