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Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside . [1] [2] The term can also refer more generally to any organic molecule that contains amino sugar substructures.
Diagram of the inner ear. Amikacin causes damage to the cochlea and vestibules. Amikacin can cause neurotoxicity if used at a higher dose or for longer than recommended. The resulting effects of neurotoxicity include vertigo, numbness, tingling of the skin (paresthesia), muscle twitching, and seizures. [9]
Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [1] There are various forms, [2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.
Gentamicin is an aminoglycoside antibiotic used to treat several types of bacterial infections. [5] This may include bone infections, endocarditis, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, and sepsis among others. [5]
Aminoglycosides such as neomycin are known for their ability to bind to duplex RNA with high affinity. [31] The association constant for neomycin with A-site RNA is in the 10 9 M −1 range. [ 32 ] However, more than 50 years after its discovery, its DNA-binding properties were still unknown.
The children were waiting for a school bus outside an apartment complex when they were seized in Fishersville. They were later tracked down to Alabama.
Acute tubular necrosis (ATN) is a medical condition involving the death of tubular epithelial cells that form the renal tubules of the kidneys.Because necrosis is often not present, the term acute tubular injury (ATI) is preferred by pathologists over the older name acute tubular necrosis (ATN). [1]
Make a big batch of these easy 3-ingredient crepes to stash in your freezer so you always have a healthy breakfast on hand. A dollop of ricotta adds protein to a store-bought crepe, while the ...