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  2. Follicular hyperplasia - Wikipedia

    en.wikipedia.org/wiki/Follicular_hyperplasia

    Follicular hyperplasia (FH) is a type of lymphoid hyperplasia and is classified as a lymphadenopathy, which means a disease of the lymph nodes. It is caused by a stimulation of the B cell compartment and by abnormal cell growth of secondary follicles .

  3. Follicular B cell - Wikipedia

    en.wikipedia.org/wiki/Follicular_B_cell

    Within the immune system, Follicular B cells (FO B cells) are a type of B cell that reside in primary and secondary lymphoid follicles (containing germinal centers) of secondary and tertiary lymphoid organs, including spleen and lymph nodes. Antibody responses against proteins are believed to involve follicular B cell pathways in secondary ...

  4. Follicular dendritic cells - Wikipedia

    en.wikipedia.org/wiki/Follicular_dendritic_cells

    - Follicular dendritic cells have round nuclei, centrally located nucleoli, bland and dispersed chromatin, and flattening of adjacent nuclear membrane. Follicular dendritic cells ( FDC ) are cells of the immune system found in primary and secondary lymph follicles ( lymph nodes ) of the B cell areas of the lymphoid tissue .

  5. Germinal center - Wikipedia

    en.wikipedia.org/wiki/Germinal_center

    Germinal centers or germinal centres (GCs) are transiently formed structures within B cell zone (follicles) in secondary lymphoid organs – lymph nodes, ileal Peyer's patches, and the spleen [1] – where mature B cells are activated, proliferate, differentiate, and mutate their antibody genes (through somatic hypermutation aimed at achieving higher affinity) during a normal immune response ...

  6. Lymphoid hyperplasia - Wikipedia

    en.wikipedia.org/wiki/Lymphoid_hyperplasia

    Follicular hyperplasia is a stimulation of the B cell compartment. It is caused by an abnormal proliferation of secondary follicles and occurs principally in the cortex without broaching the lymph node capsule. The follicles are cytologically polymorphous, are often polarized, and vary in size and shape. [3]

  7. Lymph node - Wikipedia

    en.wikipedia.org/wiki/Lymph_node

    The primary function of lymph nodes is the filtering of lymph to identify and fight infection. In order to do this, lymph nodes contain lymphocytes, a type of white blood cell, which includes B cells and T cells. These circulate through the bloodstream and enter and reside in lymph nodes. [24] B cells produce antibodies.

  8. Follicular lymphoma - Wikipedia

    en.wikipedia.org/wiki/Follicular_lymphoma

    Predominantly diffuse follicular lymphoma with 1p36 deletion usually presents with bulky enlargements of inguinal (i.e. groin) lymph nodes but may present with enlargements of the axillary (i.e. armpit) or cervical (i.e., neck) lymph nodes. In rare cases, there may be involvement of the bone marrow. In spite of the evidence of bulky and ...

  9. Lymphadenopathy - Wikipedia

    en.wikipedia.org/wiki/Lymphadenopathy

    However, inguinal lymph nodes of up to 15 mm and cervical lymph nodes of up to 20 mm are generally normal in children up to age 8–12. [ 38 ] Lymphadenopathy of more than 1.5–2 cm increases the risk of cancer or granulomatous disease as the cause rather than only inflammation or infection .

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