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In immunology, seroconversion is the development of specific antibodies in the blood serum as a result of infection or immunization, including vaccination. [1] [2] ...
Seroconversion is defined as an increase in HI (Hemagglutination-Inhibition) antibody titer of at least 4-fold, with a minimum post-vaccination HI titer of 1:40. I believe this refers to results from a Viral Hemagglutination Assay
Mechanism of class-switch recombination that allows isotype switching in activated B cells. Immunoglobulin class switching, also known as isotype switching, isotypic commutation or class-switch recombination (CSR), is a biological mechanism that changes a B cell's production of immunoglobulin from one type to another, such as from the isotype IgM to the isotype IgG. [1]
However, seroconversion was not achieved in patients who received convalescent plasma with a low neutralizing antibody titer. [32] These findings highlight a challenge of convalescent plasma therapy, namely, that recovered survivors of viral diseases may not produce high-titer neutralizing antibodies, and thus not all convalescent plasma is ...
The direct and indirect Coombs tests, also known as antiglobulin test (AGT), are blood tests used in immunohematology.The direct Coombs test detects antibodies that are stuck to the surface of the red blood cells. [1]
Studies for serial serum antibody titers to the Enterovirus 71 in blood samples taken yearly from 81 children born in 1988 was conducted from 1989 to 1994 and 1997 to 1999. They discovered an increase in EV71 seroconversion (increased susceptibility to the disease) from 3% to 11% from 1989 to 1997 and by 1997 68% of the children had evidence of ...
The mononuclear spot test or monospot test, a form of the heterophile antibody test, [1] is a rapid test for infectious mononucleosis due to Epstein–Barr virus (EBV).It is an improvement on the Paul–Bunnell test. [2]
Viral load, also known as viral burden, is a numerical expression of the quantity of virus in a given volume of fluid, including biological and environmental specimens.It is not to be confused with viral titre or viral titer, which depends on the assay.
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