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The blood–spinal cord barrier (BSCB) is a semipermeable anatomical interface that consists of the specialized small blood vessels that surround the spinal cord. While similar to the blood–brain barrier in function and morphology, it is physiologically independent and has several distinct characteristics. [1] The BSCB is involved in many ...
Vascular myelopathy (vascular disease of the spinal cord) refers to an abnormality of the spinal cord in regard to its blood supply. [1] The blood supply is complicated and supplied by two major vessel groups: the posterior spinal arteries and the anterior spinal arteries —of which the Artery of Adamkiewicz is the largest. [ 2 ]
Sectional organization of spinal cord. The spinal cord is the main pathway for information connecting the brain and peripheral nervous system. [3] [4] Much shorter than its protecting spinal column, the human spinal cord originates in the brainstem, passes through the foramen magnum, and continues through to the conus medullaris near the second lumbar vertebra before terminating in a fibrous ...
The spinal cord is protected by the vertebral column and is above the notochord, and the gastrointestinal tract is below it. [26] Nervous tissue is derived from the ectoderm, connective tissues are derived from mesoderm, and gut is derived from the endoderm. At the posterior end is a tail which continues the spinal cord and vertebrae but not ...
Neurogenic shock is a distributive type of shock resulting in hypotension (low blood pressure), often with bradycardia (slowed heart rate), caused by disruption of autonomic nervous system pathways. [1] It can occur after damage to the central nervous system, such as spinal cord injury and traumatic brain injury.
If the systolic blood pressure falls below 90 mmHg within days of the injury, blood supply to the spinal cord may be reduced, resulting in further damage. [51] Thus it is important to maintain the blood pressure which may be done using intravenous fluids and vasopressors. [105] Vasopressors used include phenylephrine, dopamine, or ...
Autonomic dysreflexia (AD) is a potentially fatal medical emergency classically characterized by uncontrolled hypertension and cardiac arrhythmia. [2] [3] [4] AD occurs most often in individuals with spinal cord injuries with lesions at or above the T6 spinal cord level, although it has been reported in patients with lesions as low as T10. [5]
The ventricular system is continuous with the central canal of the spinal cord from the fourth ventricle, [3] allowing for the flow of CSF to circulate. [ 3 ] [ 4 ] All of the ventricular system and the central canal of the spinal cord are lined with ependyma , a specialised form of epithelium connected by tight junctions that make up the blood ...