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  2. Ondansetron - Wikipedia

    en.wikipedia.org/wiki/Ondansetron

    A vial of Zofran 4 mg containing ondansetron for intravenous injection Ondansetron (marketed under the brand name Zofran) was developed in the mid-1980s by GlaxoSmithKline in London. It was granted U.S. patent protection in September 1987, [ 37 ] received a use patent June 1988, [ 38 ] and was approved by the U.S. Food and Drug Administration ...

  3. 5-HT3 antagonist - Wikipedia

    en.wikipedia.org/wiki/5-HT3_antagonist

    5-HT 3 receptor antagonist; highest affinity for 5-HT 3 receptor in this class 40 hours CYP1A2, CYP2D6, CYP3A3/4/5 [32] 0.25 mg dose Ramosetron: Benzimidazole derivative 5-HT 3 receptor antagonist 5.8 hours 300 μg/kg Tropisetron [30] Indole: 5-HT 3 receptor antagonist 5.6 hours CYP 3A3/4/5, CYP2D6: 200 μg/kg Vortioxetine: Phenylpiperazine

  4. Chemotherapy-induced nausea and vomiting - Wikipedia

    en.wikipedia.org/wiki/Chemotherapy-induced...

    These drugs block one or more of the nerve signals that cause nausea and vomiting. During the first 24 hours after chemotherapy, the most effective approach appears to be blocking the 5-HT 3 nerve signal. [10] Approved 5-HT 3 inhibitors include dolasetron (Anzemet), granisetron (Kytril, Sancuso), and ondansetron (Zofran). Their antiemetic ...

  5. North Carolina mom says pharmacy gave her 5-year-old too-high ...

    www.aol.com/news/north-carolina-mom-says...

    A study last year found that 7,000 to 9,000 people in the U.S. die from medication errors every year and that hundreds of thousands more have adverse reactions or complications that aren’t reported.

  6. 5 killed — including baby boy and toddler — in horrific ...

    www.aol.com/5-killed-including-baby-boy...

    DeKalb Police found a 43-year-old woman, a 32-year-old man, a 26-year-old woman, a 5-year-old girl, and a 1-year-old boy dead from gunshot wounds, WBS-TV 2 reported.

  7. Cyclic vomiting syndrome - Wikipedia

    en.wikipedia.org/wiki/Cyclic_vomiting_syndrome

    The average age at onset is 3–7 years, with described cases as young as 6 days and as old as 73 years. [20] Typical delay in diagnosis from onset of symptoms is 3 years. [20] Females show a slight predominance over males. [20] One study found that 3 in 100,000 five-year-olds are diagnosed with the condition. [21]

  8. 5-Year-Old Girl Hit and Killed by Truck the Day After ...

    www.aol.com/5-old-girl-hit-killed-144427519.html

    A 5-year-old girl died in an accident just after Christmas. Ariyah Marie Elias was hit by a truck as she was crossing a road in Mesa, Ariz., on Dec. 26, local station 12 News reported. Related ...

  9. Antidepressant discontinuation syndrome - Wikipedia

    en.wikipedia.org/wiki/Antidepressant...

    Methods of prevention include gradually decreasing the dose among those who wish to stop, though it is possible for symptoms to occur with tapering. [2] [6] [4] Treatment may include restarting the medication and slowly decreasing the dose. [2] People may also be switched to the long-acting antidepressant fluoxetine which can then be gradually ...

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